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Factors predicting outcomes of penile rehabilitation with udenafil 50 mg following radical prostatectomy

International Journal of Impotence Research volume 28, pages 25–30 (2016)Cite this article

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A Corrigendum to this article was published on 11 March 2016

Abstract

Udenafil is a selective phosphodiesterase type 5 inhibitor made available in recent years for the treatment of erectile dysfunction. Herein, we evaluated independent predictors of potency recovery in radical prostatectomy (RP) patients who underwent penile rehabilitation with udenafil 50 mg. One hundred and forty-three men who underwent RP were enrolled in a penile rehabilitation program using udenafil 50 mg every other day. The rate of regained potency in the study group was significantly higher compared with the recovery rate seen in patients who were not part of the penile rehabilitation program (41.3% vs 13.0%; P<0.001). On the multivariate Cox analyses, preoperative International Index of Erectile Function-5 scores (hazard ratio (HR), 1.049; P=0.040), alcohol consumption (HR, 2.043; P=0.020) and Gleason biopsy score (HR, 0.368; P=0.024) were independent preoperative predictors for potency recovery. Among post-RP variables, the use of robotic procedures (HR, 2.287; P=0.030) and pathologic stage (HR, 0.506; P=0.038) were significantly associated with potency recovery. This study identified predictive factors for the recovery of potency in patients undergoing penile rehabilitation with udenafil following RP. Our results could provide physicians with useful information for counseling RP patients and selecting optimal candidates for penile rehabilitation.

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Acknowledgements

This research was supported by the Bio and Medical Technology Development Program of the National Research Foundation (NRF) funded by the Ministry of Science, ICT and Future Planning (NRF-2014M3A9D3033887) and by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. NRF-2014R1A2A1A09006983).

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  1. T-H Kim and Y-S Ha: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Urology, School of Medicine, Chilgok Kyungpook National University, Daegu, South Korea

    T-H Kim, Y-S Ha, S H Choi, E S Yoo, B W Kim & T G Kwon

  2. Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea

    S-J Yun & W-J Kim

  3. Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA

    Y S Kwon

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Kim, TH., Ha, YS., Choi, S. et al. Factors predicting outcomes of penile rehabilitation with udenafil 50 mg following radical prostatectomy. Int J Impot Res 28, 25–30 (2016). https://doi.org/10.1038/ijir.2015.28

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