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Low to moderate alcohol consumption on serum vitamin D and other indicators of bone health in postmenopausal women in a controlled feeding study

European Journal of Clinical Nutrition volume 68, pages 1267–1270 (2014)Cite this article

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Abstract

The objective of this study was to evaluate the effect of 8 weeks of no alcohol, low (1 drink or 15 g/day) and moderate (2 drinks or 30 g/day) alcohol consumption on markers of bone health: fasting serum 25-hydroxy vitamin D (25(OH)D), osteocalcin (OC), bone-specific alkaline phosphatase (BSAP), urine deoxypyridinoline (DPD) and helical peptide (HP) in postmenopausal women (n=51). Compared with no alcohol, 1 or 2 drinks/day for 8 weeks had no significant impact on any of the bone markers. Within each alcohol group, obese women had significantly lower serum 25(OH)D and higher DPD concentrations than normal weight women. Season significantly affected the concentrations of serum 25(OH)D, but there was no significant interaction between alcohol and season on serum 25(OH)D concentrations. Low or moderate alcohol consumption for 8 weeks had no significant impact on markers of bone health in postmenopausal women.

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Acknowledgements

This study was supported by NIH and the National Cancer Institute Interagency agreement Y1-SC-8012 and the Intramural Research Program.

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Authors and Affiliations

  1. Division of Cancer Control and Population Sciences, Modifiable Risk Factors Branch, Epidemiology and Genomics Research Program, NCI, Bethesda, MD, USA

    S Mahabir

  2. Genetic Epidemiology Branch, DCEG, NCI, Bethesda, MD, USA

    S Mahabir & P R Taylor

  3. Agricultural Research Service, USDA, Beltsville, MD, USA

    D J Baer

  4. Division of Cancer Epidemiology and Genetics (DCEG), Biostatistics Branch, NCI, Bethesda, MD, USA

    R M Pfeiffer

  5. Department of Nutritional Sciences, University of Connecticut, Storrs, CT, USA

    Y Li & B A Watkins

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  1. S Mahabir
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  2. D J Baer
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  4. Y Li
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  5. B A Watkins
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  6. P R Taylor
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Correspondence to S Mahabir.

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Mahabir, S., Baer, D., Pfeiffer, R. et al. Low to moderate alcohol consumption on serum vitamin D and other indicators of bone health in postmenopausal women in a controlled feeding study. Eur J Clin Nutr 68, 1267–1270 (2014). https://doi.org/10.1038/ejcn.2014.191

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  • DOI: https://doi.org/10.1038/ejcn.2014.191

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