Xenopus articles within Nature Communications

Featured

• Article
  18 March 2024 | Open Access

  Evolutionary origin of Hoxc13-dependent skin appendages in amphibians

  Hair is the main skin appendage of mammals. Here, the authors show that claws of clawed frogs and hair contain homologous keratins and depend on the same transcription factor, Hoxc13, suggesting a common evolutionary origin of these skin appendages.

  • Marjolein Carron
  • , Attila Placido Sachslehner
  •  & Leopold Eckhart

• Article
  23 March 2021 | Open Access

  The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division

  Mechanisms triggering meiotic divisions of oocytes remain unclear. Here, the authors report that meiosis resumption relies on the timely phosphorylation of Arpp19 protein at two distinct sites, which depends on two kinases (PKA and Gwl) and a single phosphatase (PP2A-B55δ).

  • Tom Lemonnier
  • , Enrico Maria Daldello
  •  & Aude Dupré

• Article
  31 January 2020 | Open Access

  Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates

  The role of tissue mechanics in the regeneration of mucociliated epithelium in Xenopus is unclear. Here, the authors show that Xenopus ectoderm aggregates undergo epithelial-like phenotypic transition prior to differentiation of mucus-secreting goblet cells to enable regeneration.

  • Hye Young Kim
  • , Timothy R. Jackson
  •  & Lance A. Davidson

• Article
  06 March 2019 | Open Access

  Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos

  How vegfa expression is transcriptionally regulated in vivo is unclear. Here, the authors demonstrate that the ETS transcription factor Etv6 acts as a repressor and an activator of two direct regulators of vegfa expression (foxo3 and klf4, respectively) to control blood formation in Xenopus.

  • Lei Li
  • , Rossella Rispoli
  •  & Catherine Porcher

• Article
  08 September 2017 | Open Access

  interleukin-11 induces and maintains progenitors of different cell lineages during Xenopus tadpole tail regeneration

  Xenopus laevis tadpoles have maintained their ability to regenerate various organs. Here, the authors show that interleukin-11 is necessary for organ regeneration, by inducing and maintaining undifferentiated progenitors across cell lineages during Xenopus tail regeneration.

  • Hiroshi Tsujioka
  • , Takekazu Kunieda
  •  & Takeo Kubo

• Article
  04 September 2015 | Open Access

  Spinal corollary discharge modulates motion sensing during vertebrate locomotion

  Corollary discharges inform the central nervous system about impending motor activity. Here, Chagnaud et al. show that, in Xenopustadpoles, shared efferent neural pathways to the inner ear and lateral line adjust the sensitivity of sensory afferents during locomotor activity.

  • Boris P. Chagnaud
  • , Roberto Banchi
  •  & Hans Straka

• Article
  26 June 2015 | Open Access

  Structure and gating of the nuclear pore complex

  Nuclear pore complexes (NPCs) are large macromolecular assemblies that mediate the exchange of molecules between the nucleus and cytoplasm. Here the authors present a ∼20 Å cryo-EM structure of the X. laevisNPC in different states of transport to propose a model for the architecture of the NPC’s molecular gate within its central channel.

  • Matthias Eibauer
  • , Mauro Pellanda
  •  & Ohad Medalia