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| Open AccessSelective Capture of Histidine-tagged Proteins from Cell Lysates Using TEM grids Modified with NTA-Graphene Oxide
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| Open AccessHigh-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1
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| Open AccessStructural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae
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| Open AccessTetrameric structure of the restriction DNA glycosylase R.PabI in complex with nonspecific double-stranded DNA
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| Open AccessThe unravelling of the complex pattern of tyrosinase inhibition
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| Open AccessCrystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition
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| Open AccessCharacterization of WY 14,643 and its Complex with Aldose Reductase
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| Open AccessStructural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide
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| Open AccessCharacterization of the DNA dependent activation of human ARTD2/PARP2
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| Open AccessStructural basis for PPAR partial or full activation revealed by a novel ligand binding mode
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| Open AccessActivation of Xer-recombination at dif: structural basis of the FtsKγ–XerD interaction
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| Open AccessFragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production
- Angela Corvino
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| Open AccessNonlinear backbone torsional pair correlations in proteins
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| Open AccessStructural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
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| Open AccessStructure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli
- Badreddine Douzi
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| Open AccessA pre-metazoan origin of the CRK gene family and co-opted signaling network
- Yoko Shigeno-Nakazawa
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| Open AccessCrystal structures of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface
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| Open Access‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7
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| Open AccessMolecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels
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| Open AccessIndependent multimerization of Latent TGFβ Binding Protein-1 stabilized by cross-linking and enhanced by heparan sulfate
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| Open AccessStructural and histone binding ability characterization of the ARB2 domain of a histone deacetylase Hda1 from Saccharomyces cerevisiae
- Hui Shen
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| Open AccessSmoothing a rugged protein folding landscape by sequence-based redesign
- Benjamin T. Porebski
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| Open AccessMechanism of metamifop inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in Echinochloa crus-galli
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| Open AccessRational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
- Yun Zhu
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| Open AccessTransmembrane Helices Tilt, Bend, Slide, Torque, and Unwind between Functional States of Rhodopsin
- Zhong Ren
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| Open AccessHelical unwinding and side-chain unlocking unravel the outward open conformation of the melibiose transporter
- Li-Ying Wang
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| Open AccessSweeter and stronger: enhancing sweetness and stability of the single chain monellin MNEI through molecular design
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| Open AccessUtilization of paramagnetic relaxation enhancements for structural analysis of actin-binding proteins in complex with actin
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| Open AccessStructure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica
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| Open AccessFibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils
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| Open AccessStructural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family
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| Open AccessStructural basis for disruption of claudin assembly in tight junctions by an enterotoxin
- Takehiro Shinoda
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| Open AccessBiological application of Compressed Sensing Tomography in the Scanning Electron Microscope
- Matteo Ferroni
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| Open AccessFull-length model of the human galectin-4 and insights into dynamics of inter-domain communication
- Joane K. Rustiguel
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| Open AccessFörster resonance energy transfer and protein-induced fluorescence enhancement as synergetic multi-scale molecular rulers
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| Open AccessThe N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease
- Sami Kereïche
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| Open AccessBiochemical and structural characterization of the interface mediating interaction between the influenza A virus non-structural protein-1 and a monoclonal antibody
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| Open AccessMolecular basis of a novel renal amyloidosis due to N184K gelsolin variant
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| Open AccessCatalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms
- Carlos A. Tairum
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| Open AccessDistinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation
- Shunsuke Kimura
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| Open AccessThe Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus
- Falk Hillmann
- , Karine Bagramyan
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| Open AccessCrystal structures of archaeal 2-oxoacid:ferredoxin oxidoreductases from Sulfolobus tokodaii
- Zhen Yan
- , Akane Maruyama
- & Takayoshi Wakagi
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| Open AccessThe infectious particle of insect-borne totivirus-like Omono River virus has raised ridges and lacks fibre complexes
- Kenta Okamoto
- , Naoyuki Miyazaki
- & Janos Hajdu
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| Open AccessFtsZ does not initiate membrane constriction at the onset of division
- Daniel O. Daley
- , Ulf Skoglund
- & Bill Söderström
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| Open AccessCrystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
- Chiaki Okada
- , Hiroko Wakabayashi
- & Min Yao
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| Open AccessIsolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa)
- Herman Schreuder
- , Alexander Liesum
- & Mark Brönstrup
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| Open AccessStructural insights into Parkin substrate lysine targeting from minimal Miro substrates
- Julian L. Klosowiak
- , Sungjin Park
- & Sarah E. Rice
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| Open AccessG-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53
- Taniya Saha
- , Deblina Guha
- & Gaurisankar Sa