Signs and symptoms articles within Nature Reviews Cardiology

Featured

  • Review Article |

    Pulmonary and peripheral oedema are fundamental features of heart failure; however, clinical data for optimal management of these conditions are lacking. In this Review, Clark and Cleland describe the pathophysiology of both types of cardiogenic oedema and discuss how knowledge of the pathophysiology can guide treatment.

    • Andrew L. Clark
    •  & John G. F. Cleland
  • News & Views |

    The ROMICAT-II trial shows that CT coronary angiography is safe and fast for the exclusion of clinically significant obstructive coronary artery disease in low-risk patients with acute chest pain. Several issues and questions relating to the low prevalence of disease and the actual benefit to patients remain to be answered.

    • Filippo Cademartiri
    •  & Erica Maffei
  • Review Article |

    Syncope is a transient, self-terminating period of cerebral hypoperfusion that usually results from systemic hypotension. Many patients with this condition are successfully treated according to current guidelines. However, the authors identify and expertly review the current understanding of four key challenges in the characterization, diagnosis, risk stratification, and treatment of patients with suspected syncope.

    • Richard Sutton
    • , Michele Brignole
    •  & David G. Benditt
  • Opinion |

    Controversy exists as to whether the detection of myocardial edema, to quantify myocardial damage and assess myocardial salvage, is ready for clinical use or is still only practical as a research tool. In this Perspectives article, Matthias Friedrich explains his point of view on this issue—that myocardial edema imaging using magnetic resonance technology should be seen as the essential diagnostic modality of choice for patients with suspected myocardial injury by virtue of its safety, versatility, and cost-efficiency.

    • Matthias G. Friedrich