Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Imaging

CT coronary angiography in low-risk, acute chest pain

Nature Reviews Cardiology volume 9, pages 615–616 (2012)Cite this article

Subjects

The ROMICAT-II trial shows that CT coronary angiography is safe and fast for the exclusion of clinically significant obstructive coronary artery disease in low-risk patients with acute chest pain. Several issues and questions relating to the low prevalence of disease and the actual benefit to patients remain to be answered.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Bayes' theorem for diagnostic accuracy.

References

  1. Hoffmann, U. et al. Coronary CT angiography versus standard evaluation in acute chest pain. N. Engl. J. Med. 367, 299–308 (2012).

    Article  CAS  Google Scholar 

  2. Litt, H. I. et al. CT angiography for safe discharge of patients with possible acute coronary syndromes. N. Engl. J. Med. 366, 1393–1403 (2012).

    Article  CAS  Google Scholar 

  3. Nieman, K. et al. Coronary angiography with multi-slice computed tomography. Lancet 357, 599–603 (2001).

    Article  CAS  Google Scholar 

  4. Nieman, K. et al. Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation 106, 2051–2054 (2002).

    Article  Google Scholar 

  5. Goldstein, J. A. et al. A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. J. Am. Coll. Cardiol. 49, 863–871 (2007).

    Article  Google Scholar 

  6. Goldstein, J. A. et al. The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) trial. J. Am. Coll. Cardiol. 58, 1414–1422 (2011).

    Article  Google Scholar 

  7. Choi, E. K. et al. Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals. J. Am. Coll. Cardiol. 52, 357–365 (2008).

    Article  Google Scholar 

  8. Schlett, C. L. et al. Prognostic value of CT angiography for major adverse cardiac events in patients with acute chest pain from the emergency department: 2-year outcomes of the ROMICAT trial. JACC Cardiovasc. Imaging 4, 481–491 (2011).

    Article  Google Scholar 

  9. Koo, B. K. et al. Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study. J. Am. Coll. Cardiol. 58, 1989–1997 (2011).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Erasmus University Medical Center, 's Gravendijkwal 230, Rotterdam, 3015 CE, The Netherlands

    Filippo Cademartiri

  2. Department of Radiology, Cardiovascular Imaging Unit, Giovanni XXIII Clinic, Via Giovanni XXIII 7, Monastier di Treviso, 31050, Italy

    Erica Maffei

Authors
  1. Filippo Cademartiri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Erica Maffei
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Filippo Cademartiri.

Ethics declarations

Competing interests

F. Cademartiri is or has been a member of the speakers' bureau for Bracco, and a consultant for Guerbet. E. Maffei declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cademartiri, F., Maffei, E. CT coronary angiography in low-risk, acute chest pain. Nat Rev Cardiol 9, 615–616 (2012). https://doi.org/10.1038/nrcardio.2012.130

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrcardio.2012.130

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing