Sickle cell disease articles from across Nature Portfolio
Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene, which leads to deformation of red blood cells. Deformed red blood cells can obstruct small vessels and they are prone to destruction.
Latest Research and Reviews
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A unified model of human hemoglobin switching through single-cell genome editing
Nature Communications 12, 4991 -
Research
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Combining microfluidics with machine learning algorithms for RBC classification in rare hereditary hemolytic anemia
Scientific Reports 11, 13553 -
Research
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Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease
Scientific Reports 11, 11035
Classification of red cell dynamics with convolutional and recurrent neural networks: a sickle cell disease case study
Amiodarone improves anemia in a murine model of sickle cell disease and is associated with increased erythrocyte bis(monoacylglycerol) phosphate
Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease
A unified model of human hemoglobin switching through single-cell genome editing
Combining microfluidics with machine learning algorithms for RBC classification in rare hereditary hemolytic anemia
Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease
MSD buys in to emerging epigenetic cancer target