Research Highlight |
Featured
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Review Article |
Hypertension as a cardiovascular risk factor in autoimmune rheumatic diseases
Patients with autoimmune rheumatic disease have an increased risk of cardiovascular morbidity and mortality, but the mechanisms that mediate this phenomenon are not fully elucidated. In this Review, Bartoloni and colleagues highlight the relationship between hypertension and autoimmune rheumatic diseases, focusing on the immune-mediated mechanisms that influence blood-pressure control.
- Elena Bartoloni
- , Alessia Alunno
- & Roberto Gerli
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News & Views |
NSAIDs and cardiovascular risk in arthritis
In the PRECISION trial involving patients with arthritis, moderate doses of a selective cyclooxygenase 2 inhibitor were not associated with increased cardiovascular events compared with submaximal doses of nonselective NSAIDs. The balance between pain relief and cardiovascular risk with NSAIDs should be further investigated in patients with chronic inflammatory rheumatic diseases.
- Miguel A. González-Gay
- & Carlos González-Juanatey
Ibuprofen increases blood pressure in patients with arthritis