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NSAIDs and cardiovascular risk in arthritis
In the PRECISION trial involving patients with arthritis, moderate doses of a selective cyclooxygenase 2 inhibitor were not associated with increased cardiovascular events compared with submaximal doses of nonselective NSAIDs. The balance between pain relief and cardiovascular risk with NSAIDs should be further investigated in patients with chronic inflammatory rheumatic diseases.
- Miguel A. González-Gay
- & Carlos González-Juanatey
Ibuprofen increases blood pressure in patients with arthritis