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| Open AccessMisoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3
- Matthew D. Martens
- , Nivedita Seshadri
- & Joseph W. Gordon
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Article
| Open AccessPTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure
- Huizhen Wang
- , Yifan Wang
- & Aiqing Li
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Article
| Open AccessFasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways
- Ruzhou Zhao
- , Xingcheng Zhao
- & Zhibin Yu
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Review Article
| Open Access“Ryanopathies” and RyR2 dysfunctions: can we further decipher them using in vitro human disease models?
- Yvonne Sleiman
- , Alain Lacampagne
- & Albano C. Meli
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Article
| Open AccessCardiac-specific CGI-58 deficiency activates the ER stress pathway to promote heart failure in mice
- Xin Xie
- , Yi-Fan Tie
- & Ying Liu
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Article
| Open AccessMeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα
- Yu-Meng Wang
- , Yu Wu
- & Hong-Yan Wang
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Article
| Open AccessFear-of-intimacy-mediated zinc transport controls fat body cell dissociation through modulating Mmp activity in Drosophila
- Tian Wei
- , Xiaowen Ji
- & Guiran Xiao
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Article
| Open AccessDUSP6 expression is associated with osteoporosis through the regulation of osteoclast differentiation via ERK2/Smad2 signaling
- Boya Zhang
- , Putao Yuan
- & Xuewu Sun
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Article
| Open AccessGPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis
- Qian Hu
- , Yifan Zhang
- & Zhenyu Ju
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Article
| Open AccessIGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA
- Sangmi Ock
- , Woojin Ham
- & Jaetaek Kim
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Article
| Open AccessWestern diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways
- Ricardo Imbroisi Filho
- , Alan C. Ochioni
- & Patricia Zancan
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Article
| Open AccessClobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing
- Nunzio Vicario
- , Federica M. Spitale
- & Rosario Gulino
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Article
| Open AccessZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1
- Fang Wu
- , Weifeng Huang
- & Yingchuan Li
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Article
| Open AccessEffects of acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI) on body mass index
- Adrien Joseph
- , Hui Chen
- & Guido Kroemer
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Article
| Open AccessSgpl1 deletion elevates S1P levels, contributing to NPR2 inactivity and p21 expression that block germ cell development
- Feifei Yuan
- , Zhijuan Wang
- & Meijia Zhang
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Article
| Open AccessPre-emptive pharmacological inhibition of fatty acid–binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism
- Yuting Chen
- , Yue Dai
- & Hongyu Gao
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Article
| Open AccessFKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila
- Ying Zhou
- , Jian Guo
- & Youheng Wei
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Review Article
| Open AccessRoles of tRNA metabolism in aging and lifespan
- Zheng Zhou
- , Bao Sun
- & Meng Bian
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Article
| Open AccessHigh glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes
- Ben Wang
- , Yifeng Shi
- & Xiaolei Zhang
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Article
| Open AccessKv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism
- Faye L. Styles
- , Moza M. Al-Owais
- & Lee D. Roberts
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Article
| Open AccessGrowth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria
- Rajkishor Nishad
- , Dhanunjay Mukhi
- & Anil K. Pasupulati
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Article
| Open AccessThe adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells
- Yong Sook Kim
- , Hyang Hee Cho
- & Youngkeun Ahn
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Article
| Open AccessInhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney
- Marc Cougnon
- , Romain Carcy
- & Didier F. Pisani
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Article
| Open AccessSurgical procedures suppress autophagic flux in the kidney
- Carolyn N. Brown
- , Daniel Atwood
- & Charles L. Edelstein
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Article
| Open AccessGab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice
- Xinhui Wang
- , Yinan Zhao
- & Zhongxian Lu
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Article
| Open AccessPLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging
- Anda Huna
- , Audrey Griveau
- & David Bernard
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Article
| Open AccessAcute glucose influx-induced mitochondrial hyperpolarization inactivates myosin phosphatase as a novel mechanism of vascular smooth muscle contraction
- Jie Xu
- , Hongyan Yang
- & Feng Gao
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Article
| Open AccessLegumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI
- Chuan’ai Chen
- , Dekun Wang
- & Xiaoyue Tan
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Article
| Open AccessGalectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPARγ) in mice
- Jung-Hwan Baek
- , Da-Hyun Kim
- & Kyung-Hee Chun
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Article
| Open AccessVagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling
- Bin Luo
- , Yan Wu
- & Jun-ming Tang
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Article
| Open AccessSoluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages
- Jing Xu
- , Jiahui Wang
- & Jialin Liu
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Article
| Open AccessHigh-fat diet promotes renal injury by inducing oxidative stress and mitochondrial dysfunction
- Yue Sun
- , Xin Ge
- & Yan Chun Li
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Article
| Open AccessCSF1R signaling is a regulator of pathogenesis in progressive MS
- Nellwyn Hagan
- , John L. Kane
- & Dimitry Ofengeim
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Article
| Open AccessPERK controls bone homeostasis through the regulation of osteoclast differentiation and function
- Jiachao Guo
- , Ranyue Ren
- & Fengjing Guo
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Article
| Open AccessPhosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion
- Stephen Hurst
- , Fabrice Gonnot
- & Shey-Shing Sheu
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Article
| Open AccessAldosterone from endometrial glands is benefit for human decidualization
- Shu-Yun Li
- , Zhuo Song
- & Zeng-Ming Yang
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Article
| Open AccessInhibition of the long non-coding RNA NEAT1 protects cardiomyocytes from hypoxia in vitro via decreased pri-miRNA processing
- Olof Gidlöf
- , Kerstin Bader
- & David Erlinge
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Article
| Open AccessTMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities
- Zhaoji Liu
- , Jinhuan Ning
- & Yun-wu Zhang
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Article
| Open AccessAlpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
- Wenjia Li
- , Lei Yin
- & Junbo Ge
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Article
| Open AccessTherapeutic effects of rapamycin and surgical decompression in a rabbit spinal cord injury model
- Xin Zhang
- , Chuan Qin
- & Jianjun Li
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Article
| Open AccessThe circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization
- Min Zha
- , Ting Tian
- & Liji Huang
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Article
| Open AccessDual role of Ca2+-activated Cl− channel transmembrane member 16A in lipopolysaccharide-induced intestinal epithelial barrier dysfunction in vitro
- Jingru Sui
- , Chi Zhang
- & Dapeng Chen
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Article
| Open AccessHigh glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression
- Jing Wang
- , Xuefang Shen
- & Changhong Miao
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Article
| Open AccessNeddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment
- Uk-Il Ju
- , Do-Won Jeong
- & Yang-Sook Chun
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Article
| Open AccessA necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression
- Jialin Dai
- , Chonghe Zhang
- & Junhao Hu
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Article
| Open AccessElevated intracellular copper contributes a unique role to kidney fibrosis by lysyl oxidase mediated matrix crosslinking
- Yang-yang Niu
- , Ying-ying Zhang
- & Chen Yu
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Article
| Open AccessCx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells
- Delphine Hoorelbeke
- , Elke Decrock
- & Luc Leybaert
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Article
| Open AccessFerroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure
- Naoya Yamada
- , Tadayoshi Karasawa
- & Masafumi Takahashi
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Article
| Open AccessDeficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
- Anni Herranen
- , Kuu Ikäheimo
- & Ulla Pirvola