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| Open AccessInteraction analysis of ancestry-enriched variants with APOE-ɛ4 on MCI in the Study of Latinos-Investigation of Neurocognitive Aging
- Einat Granot-Hershkovitz
- , Rui Xia
- & Tamar Sofer
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Article
| Open AccessAnalytical and clinical validity of wearable, multi-sensor technology for assessment of motor function in patients with Parkinson’s disease in Japan
- Genko Oyama
- , Maximilien Burq
- & Nobutaka Hattori
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| Open AccessIntegrated multi-omics analysis of Alzheimer’s disease shows molecular signatures associated with disease progression and potential therapeutic targets
- Pradeep Kodam
- , R. Sai Swaroop
- & Ramakrishna Vadrevu
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| Open AccessBeneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease
- P. Stepanova
- , D. Kumar
- & M. H. Voutilainen
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| Open AccessDiffusion MRI approaches for investigating microstructural complexity in a rat model of traumatic brain injury
- Karthik Chary
- , Eppu Manninen
- & Alejandra Sierra
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Registered Report
| Open AccessReproducibility of cerebellar involvement as quantified by consensus structural MRI biomarkers in advanced essential tremor
- Qing Wang
- , Meshal Aljassar
- & Jean-Baptiste Poline
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Article
| Open AccessSolid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β3-42 peptide
- Illhwan Cho
- , HeeYang Lee
- & YoungSoo Kim
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| Open AccessImpairment in novelty-promoted memory via behavioral tagging and capture before apparent memory loss in a knock-in model of Alzheimer’s disease
- Tabitha Broadbelt
- , Menekse Mutlu-Smith
- & Szu-Han Wang
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| Open AccessProof of principle for the clinical use of a CE-certified automatic imaging analysis tool in rare diseases studying hereditary spastic paraplegia type 4 (SPG4)
- Tobias Lindig
- , Benjamin Bender
- & Tim W. Rattay
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Article
| Open AccessMolecular basis of C9orf72 poly-PR interference with the β-karyopherin family of nuclear transport receptors
- Hamidreza Jafarinia
- , Erik Van der Giessen
- & Patrick R. Onck
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Article
| Open AccessFerroptosis inhibition by deferiprone, attenuates myelin damage and promotes neuroprotection in demyelinated optic nerve
- Atefeh Rayatpour
- , Forough Foolad
- & Mohammad Javan
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Article
| Open AccessNaturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease
- Alyssa L. Thomas
- , Maria A. Lehn
- & Claire A. Chougnet
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| Open AccessLumbar puncture safety and tolerability in premanifest and manifest Huntington’s disease: a multi-analysis cross-sectional study
- Yara Refaat Hassan
- , Filipe Brogueira Rodrigues
- & Sarah J. Tabrizi
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Article
| Open AccessQuantification of pathological gait parameter thresholds of idiopathic normal pressure hydrocephalus patients in clinical gait analysis
- Ken Möhwald
- , Max Wuehr
- & Roman Schniepp
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Article
| Open AccessHereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperonin
- Lingling Chen
- , Aiza Syed
- & Adhitya Balaji
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Article
| Open AccessA pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration in mice
- Kavita Pal
- , Gorantla V. Raghuram
- & Indraneel Mittra
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Article
| Open AccessCombining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons
- Razan Sheta
- , Maxime Teixeira
- & Abid Oueslati
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Article
| Open AccessAlzheimer’s disease: insights from a network medicine perspective
- Federica Conte
- & Paola Paci
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Article
| Open AccessOptimized multi-echo gradient-echo magnetic resonance imaging for gray and white matter segmentation in the lumbosacral cord at 3 T
- Silvan Büeler
- , Marios C. Yiannakas
- & Gergely David
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Article
| Open AccessDYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity
- Bangfu Zhu
- , Tom Parsons
- & James J. L. Hodge
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Article
| Open AccessMonobutyrin and monovalerin improve gut–blood–brain biomarkers and alter gut microbiota composition in high-fat fed apolipoprotein-E-knockout rats
- Thao Duy Nguyen
- , Ayako Watanabe
- & Margareta Nyman
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Article
| Open AccessVenular amyloid accumulation in transgenic Fischer 344 Alzheimer’s disease rats
- J. Bishay
- , T. L. Beckett
- & J. McLaurin
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Article
| Open AccessStudy of gut microbiota alterations in Alzheimer's dementia patients from Kazakhstan
- Aiym Kaiyrlykyzy
- , Samat Kozhakhmetov
- & Sholpan Askarova
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| Open AccessMapping the association between tau-PET and Aβ-amyloid-PET using deep learning
- Gihan P. Ruwanpathirana
- , Robert C. Williams
- & Catherine E. Davey
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Article
| Open AccessPositron Emission Tomography reveals age-associated hypothalamic microglial activation in women
- Tracy Butler
- , Lidia Glodzik
- & P. David Mozley
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Article
| Open AccessFeasibility study of ultrasound-guided percutaneous laser discectomy for cervical radicular pain
- Rong Hu
- , Xiaolei Zhu
- & Haocheng Zhou
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| Open AccessVav2 is a novel APP-interacting protein that regulates APP protein level
- Youjia Zhang
- , Xiaxin Yang
- & Junfeng Wang
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| Open AccessHS3ST2 expression induces the cell autonomous aggregation of tau
- M. B. Huynh
- , N. Rebergue
- & D. Papy-Garcia
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Article
| Open AccessMultiscale entropy analysis of retinal signals reveals reduced complexity in a mouse model of Alzheimer’s disease
- Joaquín Araya-Arriagada
- , Sebastián Garay
- & Leonel E. Medina
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Article
| Open AccessTai Chi versus conventional exercise for improving cognitive function in older adults: a pilot randomized controlled trial
- Angus P. Yu
- , Edwin C. Chin
- & Parco M. Siu
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Article
| Open AccessThe differences in clinical characteristics and natural history between essential tremor and essential tremor plus
- Praween Lolekha
- , Pornpatr Dharmasaroja
- & Kongkiat Kulkantrakorn
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Article
| Open AccessSubthalamic nucleus deep brain stimulation driven by primary motor cortex γ2 activity in parkinsonian monkeys
- Olivier Darbin
- , Nobuhiko Hatanaka
- & Atsushi Nambu
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| Open AccessNegative affective burden is associated with higher resting-state functional connectivity in subjective cognitive decline
- Claudia Schwarz
- , Gloria S. Benson
- & Agnes Flöel
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| Open AccessManifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
- Laura Heath
- , John C. Earls
- & Yi Zhao
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| Open AccessNU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone
- Barış Genç
- , Mukesh Gautam
- & P. Hande Ozdinler
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| Open AccessProteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions
- Hongsun Park
- , Tomoyuki Yamanaka
- & Nobuyuki Nukina
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| Open AccessMitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy
- Mukesh Gautam
- , Aksu Gunay
- & P. Hande Ozdinler
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| Open AccessMurine glial progenitor cells transplantation and synthetic PreImplantation Factor (sPIF) reduces inflammation and early motor impairment in ALS mice
- Karolina A. Ambrożkiewicz
- , Urszula Kozłowska
- & Maciej Kurpisz
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Article
| Open AccessThe cognitive and psychiatric subacute impairment in severe Covid-19
- Pedro J. Serrano-Castro
- , Francisco J. Garzón-Maldonado
- & Fernando Rodríguez de Fonseca
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| Open AccessObsessive–compulsive personality disorder in rapid eye movement sleep behavior disorder
- Antonina Luca
- , Calogero Edoardo Cicero
- & Alessandra Nicoletti
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Article
| Open AccessAstrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden
- Celia A. McKee
- , Jiyeon Lee
- & Erik S. Musiek
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| Open AccessDiagnosis of early mild cognitive impairment using a multiobjective optimization algorithm based on T1-MRI data
- Jafar Zamani
- , Ali Sadr
- & Amir-Homayoun Javadi
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| Open AccessAssociation of metformin use with Alzheimer’s disease in patients with newly diagnosed type 2 diabetes: a population-based nested case–control study
- Junghee Ha
- , Dong-Woo Choi
- & Eosu Kim
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| Open AccessSpatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia
- Catherine A. Morgan
- , Tracy R. Melzer
- & Lynette J. Tippett
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Article
| Open AccessThe effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion
- Kadir. A. Ozcan
- , Layla T. Ghaffari
- & Aaron R. Haeusler
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| Open AccessEffect of data leakage in brain MRI classification using 2D convolutional neural networks
- Ekin Yagis
- , Selamawet Workalemahu Atnafu
- & Stefano Diciotti
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Article
| Open AccessThioredoxin-1 mediates neuroprotection of Schisanhenol against MPP+-induced apoptosis via suppression of ASK1-P38-NF-κB pathway in SH-SY5Y cells
- Hongyan Yang
- , Libo Li
- & Chao Sun
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Article
| Open AccessShotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways
- Jonas Ellegaard Nielsen
- , Bent Honoré
- & Shona Pedersen
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Article
| Open AccessTreatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitor
- Maja Zakošek Pipan
- , Sonja Prpar Mihevc
- & Gregor Majdič