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Open Access
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Transcriptional coupling of distant regulatory genes in living embryos
In Drosophila, there are extensive physical and functional associations of distant paralogous genes, including co-regulation by shared enhancers and co-transcriptional initiation over distances of nearly 250 kilobases.
- Michal Levo
- , João Raimundo
- & Michael S. Levine
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Article |
Local and global consequences of reward-evoked striatal dopamine release
Molecular and functional magnetic resonance imaging in the rat reveals distinct neuromodulatory effects of striatal dopamine that extend beyond peak release sites and activate remote neural populations necessary for performing motivated actions.
- Nan Li
- & Alan Jasanoff
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Letter |
A method for imaging and spectroscopy using γ-rays and magnetic resonance
A new imaging and spectroscopy approach combines the ability of magnetic resonance imaging to manipulate nuclear spins with the high sensitivity of γ-ray detection, enabling a greatly reduced number of nuclei to be used compared to conventional NMR signal detection.
- Yuan Zheng
- , G. Wilson Miller
- & Gordon D. Cates
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Outlook |
Inflammation: A complex problem
Multi-protein inflammasomes are being implicated in a surprising number of diseases, and researchers are keen to find out why.
- Katharine Gammon
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Outlook |
Software: The computer will see you now
From image-analysis software to lens-free microscopes that fit on a mobile phone, new tools are providing pathologists with clearer and more informative images.
- Katherine Bourzac
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Research Highlights |
Follow the lymph vessels
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News |
Glowing cells guide cancer surgeons
Tumour-specific label pinpoints malignant cells.
- Zoe Cormier
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Research Highlights |
Molecular imaging: Tumour glows out
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Technology Feature |
Probe progress
Whole-cortex in situ sequencing reveals input-dependent area identity