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| Open AccessPosition 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity
- Jennifer Solarczek
- , Thomas Klünemann
- & Anett Schallmey
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| Open AccessDemonstration of End-to-End Automation of DNA Data Storage
- Christopher N. Takahashi
- , Bichlien H. Nguyen
- & Luis Ceze
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| Open AccessTargeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model
- Laia Civit
- , Ioanna Theodorou
- & Günter Mayer
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| Open AccessAn engineered GH1 β-glucosidase displays enhanced glucose tolerance and increased sugar release from lignocellulosic materials
- Clelton A. Santos
- , Mariana A. B. Morais
- & Anete P. Souza
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| Open AccessBacteriophage T4 capsid as a nanocarrier for Peptide-N-Glycosidase F immobilization through self-assembly
- Liang Zhang
- , Pei Wang
- & Xin Liu
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| Open AccessExploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations
- Kouhei Yoshida
- , Daisuke Kuroda
- & Kouhei Tsumoto
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| Open AccessA bacterial display system for effective selection of protein-biotin ligase BirA variants with novel peptide specificity
- Jeff Granhøj
- , Henrik Dimke
- & Per Svenningsen
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| Open AccessA bio-coupling approach using a dextran-binding domain to immobilize an engineered streptavidin to Sephadex for easy preparation of affinity matrix
- Sau-Ching Wu
- , Chris Wang
- & Sui-Lam Wong
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Article
| Open AccessDesigning a whole cell bioreporter to show antioxidant activities of agents that work by promotion of the KEAP1–NRF2 signaling pathway
- Negar Mozaheb
- , Ehsan Arefian
- & Mohammad Ali Amoozegar
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| Open AccessGeneration of microalga Chlamydomonas reinhardtii expressing shrimp antiviral dsRNA without supplementation of antibiotics
- Patai Charoonnart
- , Nichakorn Worakajit
- & Vanvimon Saksmerprome
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Article
| Open AccessThe IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface
- Adam H. Barczewski
- , Michael J. Ragusa
- & Maria Pellegrini
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| Open AccessErythrocytes as bioreactors to decrease excess ammonium concentration in blood
- Eugeniy S. Protasov
- , Daria V. Borsakova
- & Elena I. Sinauridze
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| Open AccessEvolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty
- Barbara Scheuermann
- , Tanja Diem
- & Miguel A. Andrade-Navarro
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| Open AccessLigand-induced conformational switch in an artificial bidomain protein scaffold
- Corentin Léger
- , Thibault Di Meo
- & Philippe Minard
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| Open AccessA C-terminal cysteine residue is required for peptide-based inhibition of the NGF/TrkA interaction at nM concentrations: implications for peptide-based analgesics
- Andrew J. Poole
- , Laura Frigotto
- & Anna V. Hine
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| Open AccessDirected evolution of super-secreted variants from phage-displayed human Interleukin-2
- Gertrudis Rojas
- , Tania Carmenate
- & Kalet León
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| Open AccessA new recombineering system for precise genome-editing in Shewanella oneidensis strain MR-1 using single-stranded oligonucleotides
- Anna D. Corts
- , Lynn C. Thomason
- & Jeffrey A. Gralnick
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Article
| Open AccessSelection and Characterization of Anti-Dengue NS1 Single Domain Antibodies
- Lisa C. Shriver-Lake
- , Jinny L. Liu
- & Ellen R. Goldman
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Article
| Open AccessDevelopment of a highly sensitive enzyme-linked immunosorbent assay (ELISA) through use of poly-protein G-expressing cell-based microplates
- Yi-Jou Chen
- , Michael Chen
- & Kuo-Hsiang Chuang
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Article
| Open AccessComputational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein
- Sai Pooja Mahajan
- , Bunyarit Meksiriporn
- & Matthew P. DeLisa
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Article
| Open AccessEngineering the hinge region of human IgG1 Fc-fused bispecific antibodies to improve fragmentation resistance
- Saori Suzuki
- , Hiroaki Annaka
- & Ryutaro Asano
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Article
| Open AccessDevelopment of a multi-locus CRISPR gene drive system in budding yeast
- Yao Yan
- & Gregory C. Finnigan
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| Open AccessEfficient silica synthesis from tetra(glycerol)orthosilicate with cathepsin- and silicatein-like proteins
- Natalia V. Povarova
- , Nikolay A. Barinov
- & Konstantin A. Lukyanov
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| Open AccessAffinity to cellulose is a shared property among coiled-coil domains of intermediate filaments and prokaryotic intermediate filament-like proteins
- Niklas Söderholm
- , Ala Javadi
- & Linda Sandblad
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Article
| Open AccessStrategic single point mutation yields a solvent- and salt-stable transaminase from Virgibacillus sp. in soluble form
- Benedetta Guidi
- , Matteo Planchestainer
- & Francesco Molinari
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| Open AccessRerouting of NADPH synthetic pathways for increased protopanaxadiol production in Saccharomyces cerevisiae
- Jae-Eung Kim
- , In-Seung Jang
- & Ju Young Lee
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Article
| Open AccessA highly stable laccase obtained by swapping the second cupredoxin domain
- Isabel Pardo
- , David Rodríguez-Escribano
- & Susana Camarero
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| Open AccessNTnC-like genetically encoded calcium indicator with a positive and enhanced response and fast kinetics
- Natalia V. Barykina
- , Danila A. Doronin
- & Fedor V. Subach
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Article
| Open AccessEngineering a branching sucrase for flavonoid glucoside diversification
- Yannick Malbert
- , Claire Moulis
- & Magali Remaud-Simeon
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Article
| Open AccessDeciphering molecular details in the assembly of alpha-type carboxysome
- Yilan Liu
- , Xinyuan He
- & Wei Niu
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| Open AccessAn optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria
- Stephan Endres
- , Marcus Wingen
- & Thomas Drepper
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| Open AccessA phage-based assay for the rapid, quantitative, and single CFU visualization of E. coli (ECOR #13) in drinking water
- Troy C. Hinkley
- , Sangita Singh
- & Sam R. Nugen
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Article
| Open AccessHeterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
- Rasmus J. N. Frandsen
- , Paiman Khorsand-Jamal
- & Uffe H. Mortensen
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| Open AccessDevelopment of Bacillus methanolicus methanol dehydrogenase with improved formaldehyde reduction activity
- Jiyeun Yi
- , Jinhyuk Lee
- & Jung-Hoon Sohn
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| Open AccessAccelerated triacylglycerol production without growth inhibition by overexpression of a glycerol-3-phosphate acyltransferase in the unicellular red alga Cyanidioschyzon merolae
- Satoshi Fukuda
- , Eri Hirasawa
- & Sousuke Imamura
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| Open AccessDeveloping dual herbicide tolerant transgenic rice plants for sustainable weed management
- Dhirendra Fartyal
- , Aakrati Agarwal
- & M. K. Reddy
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| Open AccessEfficient targeted integration into the bovine Rosa26 locus using TALENs
- Ming Wang
- , Zhaolin Sun
- & Yunping Dai
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| Open AccessImproving catalytic activity of the Baeyer–Villiger monooxygenase-based Escherichia coli biocatalysts for the overproduction of (Z)-11-(heptanoyloxy)undec-9-enoic acid from ricinoleic acid
- Ji-Min Woo
- , Eun-Yeong Jeon
- & Jin-Byung Park
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| Open AccessStructural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
- Seiji Negoro
- , Naoki Shibata
- & Yoshiki Higuchi
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| Open AccessTransient AID expression for in situ mutagenesis with improved cellular fitness
- Talal Salem Al-Qaisi
- , Yu-Cheng Su
- & Steve R. Roffler
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| Open AccessMetabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes
- Young Bok (Abraham) Kang
- , Jinsu Eo
- & O. Berk Usta
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| Open AccessEngineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5
- Yosuke Hashimoto
- , Wei Zhou
- & Hiroyuki Takeda
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| Open AccessIgG-single-chain TRAIL fusion proteins for tumour therapy
- Martin Siegemund
- , Felix Schneider
- & Roland E. Kontermann
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| Open AccessStructure-guided Discovery of Dual-recognition Chemibodies
- Alan C. Cheng
- , Elizabeth M. Doherty
- & Zhulun Wang
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| Open AccessAffimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells
- Anna Lopata
- , Ruth Hughes
- & Michelle Peckham
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| Open AccessMolecular design of radiocopper-labelled Affibody molecules
- Vladimir Tolmachev
- , Tove J. Grönroos
- & Amelie Eriksson Karlström
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| Open AccessCrystal structure of Bacillus cereus flagellin and structure-guided fusion-protein designs
- Meong Il Kim
- , Choongdeok Lee
- & Minsun Hong
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| Open AccessAffinity maturation of humanized anti-epidermal growth factor receptor antibody using a modified phage-based open sandwich selection method
- Hideaki Sanada
- , Kazuki Kobayashi
- & Izumi Kumagai
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| Open AccessEngineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity
- Mary-Carmen Torres-Quintero
- , Isabel Gómez
- & Alejandra Bravo