Medical research articles within Nature

Featured

  • Editorial |

    The great achievements of vaccines are not consigned to the past.

  • Career Brief |

    Federal grants won't evaporate for US biomedical researchers in 2011.

  • News & Views |

    Heart failure is characterized by weakened contractions of heart muscle. A drug that directly activates the key force-generating molecule in this muscle may be a valuable tool to strengthen the failing heart.

    • Donald M. Bers
    •  & Samantha P. Harris

  • Comment |

    Calls in Canada for trials of a contentious treatment for multiple sclerosis illustrate how social media can affect research priorities, say Roger Chafe and his colleagues.

    • Roger Chafe
    • , Karen B. Born
    •  & Andreas Laupacis

  • News & Views |

    The placenta does not only act as the essential link between the developing embryo and its mother. Unexpectedly, it is also a source of serotonin — a neurotransmitter that is crucial for embryonic brain development. See Letter p.347

    • Ron McKay

  • News Feature |

    Scientists reviving a decades-old technique for brain stimulation have found that it can boost learning. So what else can be done with some wires and a nine-volt battery?

    • Douglas Fox

  • Feature |

    San Diego's diverse corporate science portfolio offers opportunities for open-minded scientists hoping to escape stagnation in academia.

    • Karen Kaplan

  • News & Views |

    A common dietary component that some people even take as a supplement is converted by the gut microbiota to harmful metabolites linked to heart disease. This finding has cautionary implications. See Article p.57

    • Kimberly Rak
    •  & Daniel J. Rader

  • Technology Feature |

    For years, scientists have struggled to reconstruct tissues and organs by combining cells and nanotechnology. These devices are now edging from cool concept to practical application.

    • Monya Baker

  • Comment |

    A radical restructure is the only way to solve the systemic problems of the world's biggest funder of biomedical research, argues Michael M. Crow.

    • Michael M. Crow

  • Career Brief |

    US biomedical research risks losing top talent, says NIH director.

  • Outlook |

    Despite our relative wealth of knowledge about the causes of cancer, the disease persists — and the burden is worsening. Prevention demands political will, ample funding and a change in mindset.

    • Tiffany O'Callaghan

  • News & Views |

    Anticancer therapies can impair male fertility. Whereas men can opt to freeze their sperm before treatment, young boys don't produce mature sperm and so lack this choice. Work in mice offers hope for such patients. See Letter p.504

    • Marco Seandel
    •  & Shahin Rafii

  • Editorial |

    Scientists studying diseases should be motivated by patients, but not led by them.

  • News & Views |

    The hormone progesterone rapidly activates intracellular signalling in human sperm, regulating key aspects of their physiology. An ion channel unique to the sperm tail seems to relay progesterone's signal. See Letters p.382 & p.387 See Clarification  p.598

    • Steve Publicover
    •  & Christopher Barratt

  • News & Views |

    New clinical trials report the efficacy of two mechanism-based therapies for treating human pancreatic neuroendocrine tumours. Studies in mouse models have contributed to these success stories, and continue to do so.

    • David Tuveson
    •  & Douglas Hanahan

  • News |

    Some senior scientists feel neglected by the National Institutes of Health's grant formula.

    • Kendall Powell

  • News Feature |

    When Judy Mikovits found links between chronic fatigue syndrome and a virus, the world took notice. Now, she's caught between the patients who believe her work and the researchers who don't.

    • Ewen Callaway

  • News & Views |

    The vitamin-A metabolite retinoic acid normally favours immune tolerance in the gut. But in coeliac disease — an intestinal inflammatory disorder due to adverse reactivity to a dietary protein — it may do just the opposite. See Letter p.220

    • Craig L. Maynard
    •  & Casey T. Weaver

  • Editorial |

    Birth-cohort studies offer invaluable data on the links between childhood development and later life, but today's efforts could learn something from a pioneering project that turns 65 this week.

  • News |

    Translational-science centre remains on the fast track, despite concerns about upheaval.

    • Meredith Wadman

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