Featured
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Review Article
| Open AccessThe implications of FASN in immune cell biology and related diseases
- Yucai Xiao
- , Yonghong Yang
- & Guanjun Dong
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Article
| Open AccessPalmitate induces integrated stress response and lipoapoptosis in trophoblasts
- Prakash Kumar Sahoo
- , Chandan Krishnamoorthy
- & Sathish Kumar Natarajan
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Article
| Open AccessElovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases
- Jorgelina M. Calandria
- , Surjyadipta Bhattacharjee
- & Nicolas G. Bazan
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Article
| Open AccessFatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation
- Seungyeon Yang
- , Sunsook Hwang
- & Seung Min Jeong
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Article
| Open AccessA Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission
- Mai N. Nguyen
- , Dibyendu Chakraborty
- & Steven J. Pittler
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Article
| Open AccessSmooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
- Dan-Dan Zhang
- , Yu Song
- & Mei Han
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Article
| Open AccessSulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis
- Yuting Yan
- , Yan Zhou
- & Wei Wu
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Article
| Open AccessMitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
- Peina Wang
- , Yanmei Cui
- & Yan-Zhong Chang
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Article
| Open AccessWithaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3
- Yangliu Xia
- , Ping Wang
- & Tingting Yan
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Article
| Open AccessAcid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis
- Faisal Thayyullathil
- , Anees Rahman Cheratta
- & Sehamuddin Galadari
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Article
| Open AccessAcyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition
- Yunchang Liu
- , Liping Zeng
- & Hong Wang
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Article
| Open AccessActivating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1
- Bin Sun
- , Yongkang Jiang
- & Bin Wang
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Article
| Open AccessTNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice
- Franziska Wandrer
- , Stephanie Liebig
- & Heike Bantel
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Review Article
| Open AccessLipid droplets: platforms with multiple functions in cancer hallmarks
- André L. S. Cruz
- , Ester de A. Barreto
- & Patricia T. Bozza
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Article
| Open Accessα-Linolenic acid but not linolenic acid protects against hypertension: critical role of SIRT3 and autophagic flux
Schematic diagram of the mechanisms whereby α-linolenic acid protects against endothelial dysfunction and hypertension.
- Guohua Li
- , Xinpei Wang
- & Jia Li
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Article
| Open AccessRegulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition
- Sherry S. Agabiti
- , Jin Li
- & Andrew J. Wiemer
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Article
| Open AccessPPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation
- Lei Tong
- , Long Wang
- & Zhiguo Zhang
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Original Article
| Open AccessSphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain
- Dan-Dan Song
- , Tong-Tong Zhang
- & Rui Sheng
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Original Article
| Open AccessInflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression
- Shin Kasai
- , Yoshiyuki Furuichi
- & Kanji Sugita
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News and Commentary
| Open AccessThe lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells
- Amy A Baxter
- , Ivan KH Poon
- & Mark D Hulett
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Original Article
| Open AccessAugmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis
- Liane Jennifer Bailey
- , Sruthi Alahari
- & Isabella Caniggia
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Original Article
| Open AccessPhospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells
- Ming Cai
- , Jingquan He
- & Guangwei Du
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Original Article
| Open AccessC2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro
- R Stanzione
- , S Sciarretta
- & S Rubattu
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Original Article
| Open AccessSGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α
- D Pastore
- , D Della-Morte
- & D Lauro
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Original Article
| Open AccessUncoupling Neogenin association with lipid rafts promotes neuronal survival and functional recovery after stroke
- A P Shabanzadeh
- , N G Tassew
- & P P Monnier
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Original Article
| Open AccessArachidonic acid promotes skin wound healing through induction of human MSC migration by MT3-MMP-mediated fibronectin degradation
- S Y Oh
- , S-J Lee
- & H J Han
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Original Article
| Open AccessLoss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances
- J T Vollrath
- , A Sechi
- & A Goswami
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Original Article
| Open AccessApolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein
- J Galindo-Moreno
- , R Iurlaro
- & C Muñoz-Pinedo
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Review
| Open AccessThe pleiotropic roles of sphingolipid signaling in autophagy
- Y Li
- , S Li
- & L Xiong
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Original Article
| Open AccessLipopolysaccharide sensitized male and female juvenile brains to ionizing radiation
- M Kalm
- , K Roughton
- & K Blomgren
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Original Article
| Open AccessPro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis
- Y K Adlakha
- , S Khanna
- & N Saini
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Original Article
| Open AccessCalcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents
- A Kmit
- , R van Kruchten
- & K Kunzelmann
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Original Article
| Open AccessFunctional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure
- S Dinkla
- , K Wessels
- & G J C G M Bosman
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Original Article
| Open AccessMS-275 sensitizes osteosarcoma cells to Fas ligand-induced cell death by increasing the localization of Fas in membrane lipid rafts
- K Rao-Bindal
- , Z Zhou
- & E S Kleinerman
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Original Article
| Open AccessSkeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity
- K P Tamilarasan
- , H Temmel
- & G Hoefler
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Original Article
| Open AccessCeramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine
- J J Gills
- , C Zhang
- & P A Dennis
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Original Article
| Open AccessInvolvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria
- F Mollinedo
- , M Fernández
- & C Gajate
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Original Article
| Open AccessS1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism
- A Kumar
- , B Oskouian
- & J D Saba
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Original Article
| Open AccessGiant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity
- O Jalmar
- , A J García-Sáez
- & P X Petit
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Original Article
| Open AccessPrenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development
- G Wang
- & E Bieberich