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| Open AccessMulti-study reanalysis of 2,213 acute myeloid leukemia patients reveals age- and sex-dependent gene expression signatures
- Raeuf Roushangar
- & George I. Mias
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| Open AccessInhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells
- Juan Bautista Menendez-Gonzalez
- , Samantha Sinnadurai
- & Neil P. Rodrigues
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| Open AccessThe FLT3-ITD mutation and the expression of its downstream signaling intermediates STAT5 and Pim-1 are positively correlated with CXCR4 expression in patients with acute myeloid leukemia
- Tingyong Cao
- , Nenggang Jiang
- & Qin Zheng
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Article
| Open AccessProgressive hyperleukocytosis is a relevant predictive marker for differentiation syndrome, early death, and subsequent relapse in acute promyelocytic leukemia
- Jae-Ho Yoon
- , Hee-Je Kim
- & Jong Wook Lee
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| Open AccessAllelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia
- Aarif M. N. Batcha
- , Stefanos A. Bamopoulos
- & Tobias Herold
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Article
| Open AccessHyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines
- Silvina Lompardía
- , Mariángeles Díaz
- & Silvia Hajos
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| Open AccessMicroRNA signature refine response prediction in CML
- Raquel Alves
- , Ana Cristina Gonçalves
- & Ana Bela Sarmento-Ribeiro
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Article
| Open AccessRetinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells
- Thomas T. Huynh
- , Mohammad Sultan
- & Paola Marcato
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Article
| Open AccessSOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness
- Chi Huu Nguyen
- , Tobias Glüxam
- & Gerwin Heller
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| Open AccessSelection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells
- Yacong An
- , Yan Hu
- & Xian-Da Yang
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Article
| Open AccessHemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species
- Eleonora Turrini
- , Elena Catanzaro
- & Carmela Fimognari
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Article
| Open AccessDysbiosis patterns during re-induction/salvage versus induction chemotherapy for acute leukemia
- Armin Rashidi
- , Thomas Kaiser
- & Christopher Staley
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Article
| Open AccessOligomeric self-association contributes to E2A-PBX1-mediated oncogenesis
- Chiou-Hong Lin
- , Zhong Wang
- & Michael L. Cleary
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Article
| Open AccessCopy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia
- Elisabeth M. P. Steeghs
- , Judith M. Boer
- & Monique L. den Boer
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Article
| Open AccessTracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion
- Sujatha Chilakala
- , Ye Feng
- & Yan Xu
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Article
| Open AccessHexamethylene bisacetamide impairs NK cell-mediated clearance of acute T lymphoblastic leukemia cells and HIV-1-infected T cells that exit viral latency
- Erica Giuliani
- , Maria Giovanna Desimio
- & Margherita Doria
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Article
| Open AccessIntegrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures
- Michael P. Schroeder
- , Lorenz Bastian
- & Claudia D. Baldus
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Article
| Open AccessEffect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo
- Nicole D. Vincelette
- , Husheng Ding
- & Scott H. Kaufmann
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Article
| Open AccessNovel mutations in the kinase domain of BCR-ABL gene causing imatinib resistance in chronic myeloid leukemia patients
- Chodimella Chandrasekhar
- , Pasupuleti Santhosh Kumar
- & Potukuchi Venkata Gurunadha Krishna Sarma
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Article
| Open AccessFibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia
- Isabel S. Jerchel
- , Alex Q. Hoogkamer
- & Monique L. den Boer
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Article
| Open AccessIL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival
- Yiqian Wang
- , Lisa Richter
- & R. Katherine Hyde
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Article
| Open AccessEvaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation
- Kodappully S. Siveen
- , Kirti S. Prabhu
- & Fouad Azizi
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Article
| Open AccessBCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo
- Cédric Schleiss
- , Wassila Ilias
- & Laurent Vallat
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Article
| Open AccessPolymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms
- Maria Cabezas
- , Lydia García-Quevedo
- & Gemma Armengol
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Article
| Open AccessCryopreservation of primary B cells minimally influences their signaling responses
- Johanne U. Hermansen
- , Geir E. Tjønnfjord
- & Sigrid S. Skånland
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Article
| Open AccessMidostaurin reduces Regulatory T cells markers in Acute Myeloid Leukemia
- Lucas Gutierrez
- , Miran Jang
- & Houda Alachkar
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Article
| Open AccessIron removal enhances vitamin C-induced apoptosis and growth inhibition of K-562 leukemic cells
- Mitsuyo Tsuma-Kaneko
- , Masakazu Sawanobori
- & Hiroshi Kawada
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Article
| Open AccessPre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein
- Eun Ji Joo
- , Brian R Wasik
- & Nora Heisterkamp
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Article
| Open AccessTransposable Element Expression in Acute Myeloid Leukemia Transcriptome and Prognosis
- Anthony R. Colombo
- , Timothy Triche Jr.
- & Giridharan Ramsingh
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Article
| Open AccessASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation
- Makoto Saika
- , Daichi Inoue
- & Susumu Goyama
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Article
| Open AccessRepression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML
- Eimear O’ Reilly
- , Sukhraj Pal S. Dhami
- & Eva Szegezdi
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Article
| Open AccessCharacterizing Deformability of Drug Resistant Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells Using Acoustic Tweezers
- Hsiao-Chuan Liu
- , Eun Ji Gang
- & Yong-Mi Kim
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Article
| Open AccessGenome wide mapping of ETV6 binding sites in pre-B leukemic cells
- Benjamin Neveu
- , Maxime Caron
- & Daniel Sinnett
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Article
| Open AccessMetabolic abnormalities in adult T-cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy
- Takashi Oka
- , Hajime Mizuno
- & Atae Utsunomiya
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Article
| Open AccessAlteration of Serum Free Fatty Acids are Indicators for Progression of Pre-leukaemia Diseases to Leukaemia
- Ayesha Khalid
- , Amna Jabbar Siddiqui
- & Syed Ghulam Musharraf
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Article
| Open AccessEfficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control
- Purvi M. Kakadia
- , Neil Van de Water
- & Stefan K. Bohlander
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Article
| Open AccessPharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase
- Norihito Shibata
- , Kenichiro Shimokawa
- & Mikihiko Naito
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Article
| Open AccessCharacterization of Mutations in the Mitochondrial Encoded Electron Transport Chain Complexes in Acute Myeloid Leukemia
- Sharon Wu
- , Mojtaba Akhtari
- & Houda Alachkar
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Article
| Open AccessA novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity
- Maria Yusenko
- , Anke Jakobs
- & Karl-Heinz Klempnauer
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Article
| Open AccessQuantitative prediction of long-term molecular response in TKI-treated CML – Lessons from an imatinib versus dasatinib comparison
- Ingmar Glauche
- , Matthias Kuhn
- & Ingo Roeder
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Article
| Open AccessDesign and MinION testing of a nanopore targeted gene sequencing panel for chronic lymphocytic leukemia
- Paola Orsini
- , Crescenzio F. Minervini
- & Francesco Albano
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Article
| Open AccessMediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia
- Roman Hornung
- , Vindi Jurinovic
- & Anne-Laure Boulesteix
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Article
| Open AccessThe histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
- Yaser Heshmati
- , Shabnam Kharazi
- & Julian Walfridsson
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Article
| Open AccessInhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine
- Maria Omsland
- , Cynthia Pise-Masison
- & Vibeke Andresen
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Article
| Open AccessT315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system
- Minori Tamai
- , Takeshi Inukai
- & Kanji Sugita
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Article
| Open AccessRational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT
- Jaideep B. Bharate
- , Nicholas McConnell
- & Hong-yu Li
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Article
| Open AccessA large-scale RNA interference screen identifies genes that regulate autophagy at different stages
- Sujuan Guo
- , Kevin J. Pridham
- & Zhi Sheng
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Article
| Open AccessTargeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles
- Tamoghna Mandal
- , Michaela Beck
- & Christian Buske
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Article
| Open AccessHigh STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia
- Elisabeth M. P. Steeghs
- , Marjolein Bakker
- & Monique L. den Boer