Laboratory techniques and procedures

Laboratory techniques and procedures are performed on patient specimens to detect biomarkers and diagnose diseases. Blood, urine, semen or tissue samples can be analysed using biochemical, microbiological and cytological methods.

Latest Research and Reviews

News and Comment

  • News and Views |

    Antibodies against phosphatidylserine–prothrombin complexes (PS–PT) are one type of antiphospholipid antibody that is responsible for lupus anticoagulant activity. Anti-PS–PT antibodies are not currently included in the classification criteria for antiphospholipid syndrome (APS), but should they replace lupus anticoagulant testing to improve the diagnosis of APS?

    • Yuichiro Fujieda
    •  & Tatsuya Atsumi
  • News and Views |

    Current recommendations for diagnosing diabetes mellitus require confirmation of an abnormal fasting plasma glucose level or elevated HbA1c level, with repeated testing. Elizabeth Selvin and colleagues have examined the effectiveness of measuring plasma levels of glucose and HbA1c simultaneously for diagnosing diabetes mellitus and conclude that the confirmed combination is acceptable.

    • David M. Nathan
  • News and Views |

    Different methods for detecting circulating tumour cells (CTCs) in the blood of patients with cancer yield distinct results with regard to cell counts and CTC subpopulations. This observation underlines the urgent need for comprehensive standardization and validation of novel CTC technologies in order to facilitate their introduction into clinical practice.

    • Claudia Hille
    •  & Klaus Pantel