Health care articles within Nature

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  • Regions |

    Jeffrey Koplan, vice-president for global health at Emory University and former director of the Centers for Disease Control and Prevention (CDC), both in Atlanta, discusses Georgia's life-sciences and public-health sectors.

    • Karen Kaplan

  • Regions |

    Georgia looks to capitalize on its public-health and bioscience strengths.

  • Opinion |

    Although largely unregulated, genetic tests are increasingly used to diagnose conditions, map ancestry or predict disease risk. In this, the first of two related pieces, Arthur L. Beaudet advocates the US Food and Drug Administration banning direct-to-consumer medical tests but leaving the analysis of clinical diagnostics to specialists. In the second, Gail Javitt argues that the agency should implement a regulatory framework for all health-related tests.

    • Arthur L. Beaudet

  • Opinion |

    Although largely unregulated, genetic tests are increasingly used to diagnose conditions, map ancestry or predict disease risk. In this, the second of two related pieces, Gail Javitt argues that the US Food and Drug Administration should implement a regulatory framework for all health-related tests. In the first, Arthur L. Beaudet advocates the agency banning direct-to-consumer medical tests but leaving the analysis of clinical diagnostics to specialists.

    • Gail Javitt

  • News |

    Farmers and scientists struggle to keep up with needs of ambitious medicine-subsidy programme.

    • Richard Van Noorden

  • News & Views |

    Work on stem cells is one of the hottest research areas in biology. But are such studies of any therapeutic value? Fortunately, yes, as is evident from successes in treating blindness.

    • Elena Ezhkova
    •  & Elaine Fuchs

  • Article |

    PPARγ ligands are used to control diabetes, but their anti-diabetic actions are puzzling. Here the authors show that phosphorylation of PPARγ by cyclin-dependent kinase 5 (Cdk5) in mice is linked to obesity induced by high-fat feeding, and that inhibition of the effect in humans by the drug rosiglitazone is closely associated with its anti-diabetic effects. Several anti-diabetic PPARγ ligands directly inhibit the effect, and thus support a more normal non-diabetic pattern of gene expression.

    • Jang Hyun Choi
    • , Alexander S. Banks
    •  & Bruce M. Spiegelman

  • Editorial |

    The controversy surrounding diabetes drugs highlights the importance of comparative studies.

  • News & Views |

    Antidiabetic drugs that activate the protein PPARγ had a bright start but soon lost their appeal because of undesirable side effects. Subtle modifications may once again make them suitable for treating diabetes.

    • Riekelt H. Houtkooper
    •  & Johan Auwerx

  • Outlook |

    • Apoorva Mandavilli

  • Outlook |

    For many people in the developed world HIV is no longer the death sentence it once was. Paroma Basu explores the consequences of complacency.

    • Paroma Basu

  • Outlook |

    No single strategy alone is likely to thwart HIV's spread. Researchers are turning to 'prevention packages' of two or more approaches, Cassandra Willyard reports.

    • Cassandra Willyard

  • Outlook |

    Co-infection with HIV and tuberculosis is a potent combination. Amy Maxmen investigates the impact of this deadly duo.

    • Amy Maxmen

  • Outlook |

    HIV keeps the immune system in a hyperactive state, gradually leading to its ruin, reports Emma Marris.

    • Emma Marris

  • Outlook |

    There is more to combating HIV in the developing world than providing affordable drugs. T. V. Padma looks at the innovative new strategies being employed.

    • T. V. Padma

  • Outlook |

    A Cambodian group has developed a pioneering community-based approach to HIV and TB care and research. Amy Maxmen describes how this powerful model is being expanded to other war-torn countries.

    • Amy Maxmen

  • Outlook |

    Researchers hope to unlock the secrets of the select few who rein in, or even resist, HIV infection, says Bijal Trivedi.

    • Bijal Trivedi

  • Outlook |

    Specialization has its place, but truly innovative advances in HIV research usually come from interdisciplinary efforts, reports Unmesh Kher.

    • Unmesh Kher

  • Outlook |

    There is a formidable arsenal of drugs available to treat HIV. Virginia Hughes finds that, for the first time in years, there is also renewed hope of a cure.

    • Virginia Hughes

  • Books & Arts |

    Awa-Marie Coll-Seck enjoys a hard-hitting history of malaria, but takes issue with its contention that current eradication strategies are repeating the errors of the past.

    • Awa-Marie Coll-Seck

  • Editorial |

    Much tighter regulations are needed to reap the full benefits of stem-cell treatments.

  • News Feature |

    When emergencies happen in remote settings, field researchers can be left with little recourse. Erik Vance meets a man trying to change that.

    • Erik Vance

  • Feature |

    Chagas disease is a disease of Latin America. In spite of extensive control efforts it is so prevalent that in some areas, such as within the Gran Chaco (see Chagas disease in the Chaco, on page S18), one person in 16 is infected.

  • Feature |

    Anna Petherick investigates the nature of Chagas disease and how its management varies across Latin America.

    • Anna Petherick

  • Feature |

    It is 101 years since Carlos Chagas discovered the parasite responsible for the disease that now bears his name. What progress has been made since this discovery? Here Julie Clayton gives the low-down on Chagas disease.

    • Julie Clayton

  • Feature |

    Energized individuals have worked hard to raise awareness. But politicians have not always listened.

    • Anna Petherick

  • Editorial |

    We must learn lessons from the handling of the flu pandemic to improve future research and public-health responses to emerging diseases, but retrospective hindsight and recriminations are not the answer.

  • Feature |

    Researching disease transmission in poor, rural settings is part scientific inquiry, part diplomacy.

    • Anna Petherick

  • Opinion |

    Endemic Chagas disease began as a neglected disease of poor, rural and forgotten populations. Its spread from Latin America to non-endemic countries is a new worldwide challenge, say José Rodrigues Coura and Pedro Albajar Viñas.

    • José Rodrigues Coura
    •  & Pedro Albajar Viñas

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