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News |
Nature’s biggest news stories of 2022
From Russia’s invasion of Ukraine to predicting protein structures with AI and transplanting pig organs into people, our news editors choose the defining moments in science this year.
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News Explainer |
RSV wave hammers hospitals — but vaccines and treatments are coming
As the respiratory illness helps to fuel a ‘tripledemic’, Pfizer and GSK race to get jabs approved.
- Rachel Fairbank
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Editorial |
Missing data mean we’ll probably never know how many people died of COVID
Huge discrepancies in estimates of excess mortality reveal not just how difficult the calculations are, but how far the world has to go in recording how people die.
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News & Views |
Global estimates of excess deaths from COVID-19
Estimating the number of deaths attributable to COVID-19 around the world is a complex task — as highlighted by one attempt to measure global excess mortality in 2020 and 2021.
- Enrique Acosta
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Nature Podcast |
COVID deaths: three times the official toll
An estimate of the deaths associated with COVID-19, and the lack of ethnic diversity in UK academia.
- Nick Petrić Howe
- & Benjamin Thompson
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Outline |
How to vaccinate the world next time
Experts discuss the lessons learnt from COVID-19 and the challenge of preparing the world for the next global pandemic.
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World View |
Even after COVID, the world’s vaccine strategy is failing
Without a global, publicly funded strategy, the market will fail to deliver vaccines to stop pandemics before they surge.
- Seth Berkley
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News Q&A |
Fauci responds to Musk’s Twitter attack and rates world’s COVID response
Public-health leader advises early-career researchers ‘not to be deterred’ by public vitriol.
- Max Kozlov
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News |
Flu causes huge spike in child hospitalizations in Canada
Seasonal influenza is hitting North America hard owing to a lack of exposure and dominance of the virulent strain H3N2.
- Nicola Jones
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News |
China is relaxing its zero-COVID policy — here’s what scientists think
Researchers say the rule changes will lead to a rise in infections that could overwhelm hospitals.
- Smriti Mallapaty
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News Explainer |
Why is strep A surging — and how worried are scientists?
The tragic deaths of 13 children in England and an unusual rise in autumn cases have put researchers on alert.
- Heidi Ledford
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News |
Largest-ever analysis finds genetic links to smoking and drinking
A study involving almost 3.4 million people with diverse ancestries has identified thousands of genetic variants associated with tobacco and alcohol use.
- Miryam Naddaf
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News |
Surprising Omicron origins study comes under scrutiny
Sequences of early forms of the fast-spreading variant reported to have been circulating in West Africa could have resulted from contamination.
- Smriti Mallapaty
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Book Review |
How smallpox inoculation united America
Government responsibility for public health shaped the fledgling nation’s concepts of freedom.
- Heidi Ledford
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Research Briefing |
A liver drug reduces SARS-CoV-2 entry into cells
A widely used drug called UDCA reduces SARS-CoV-2 infection in human organoid structures, animals and human organs maintained outside the body. Individuals using UDCA for liver conditions are less likely to develop severe COVID-19 than are people who did not use it. UDCA treatment could help to protect people with suppressed immune systems and offer protectionagainst vaccine-resistant variants.
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News Feature |
These monkeypox researchers warned that the disease would go global
A Nigerian disease-surveillance expert and a US epidemiologist have been tracking monkeypox for years. Can their insights help to stop its spread and prevent future outbreaks?
- Paul Adepoju
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News Explainer |
Can China avoid a wave of deaths if it lifts strict zero COVID policy?
Vaccinating more older people, stocking up on antiviral drugs and expanding hospital facilities would help to ease the transition away from zero COVID.
- Smriti Mallapaty
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News |
Heralded Alzheimer’s drug works — but safety concerns loom
Eisai and Biogen share clinical trial data confirming that lecanemab slows mental decline, amid reports of potentially related deaths.
- McKenzie Prillaman
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Correspondence |
Mental health and nature: more implementation research needed
- Ralf Buckley
- , Linsheng Zhong
- & Mary-Ann Cooper
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Career Feature |
Tackle systemic racism to diversify health care and clinical research
Solving structural-racism problems in health will require everyone, from community members to heads of university departments, to be engaged.
- Virginia Gewin
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Correspondence |
Food: use artificial intelligence to create new proteins
- Selena Ahmed
- , Maya Rajasekheren
- & Tracy Shafizadeh
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News |
How the Great Depression shaped people’s DNA
Epigenetics study finds that children born during the historic recession have markers of accelerated ageing later in life.
- Freda Kreier
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Clinical Briefing |
An autoimmune mechanism underlying a fatal form of heart inflammation
Immune-related adverse events are a limiting factor in the use of cancer immunotherapies but the mechanisms and risk factors are largely unknown. T cells that recognize a heart-muscle protein mediate an immunotherapy-related condition called myocarditis.
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World View |
To beat Ebola in Uganda, fund what worked in Liberia
Enlist community members to find and support cases — trust is crucial to containment.
- Mosoka P. Fallah
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Editorial |
Farming feeds the world. We desperately need to know how to do it better
Interventions designed to improve agricultural practices often lack a solid evidence base. A new initiative could change that.
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Correspondence |
WHO principles speed up ethical sharing of pathogen genomic data
- Vasee Moorthy
- , Oliver Morgan
- & Soumya Swaminathan
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Where I Work |
Braving stings to put jellyfish on the menu
Antonella Leone catches jellyfish off the coast of Italy to study them as potential sources of medicine and food.
- James Mitchell Crow
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News Round-Up |
Higgs boson carbon emissions and a COVID nasal spray
The latest science news, in brief.
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Nature Index |
US agency seeks to phase out animal testing
The Food and Drug Administration commits to exploring alternative methods to replace laboratory animals in developing new drugs and products.
- Rachel Nuwer
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Article
| Open AccessA multinational Delphi consensus to end the COVID-19 public health threat
A diverse, multidisciplinary panel of 386 experts in COVID-19 response from 112 countries provides health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.
- Jeffrey V. Lazarus
- , Diana Romero
- & Anne Øvrehus
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News |
COVID vaccine hoarding might have cost more than a million lives
Low- and middle-income nations would have had lower death rates if vaccines had been shared more equitably.
- Heidi Ledford
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News |
Could a nose spray a day keep COVID away?
Scientists are working on fast-acting nasal sprays to block coronavirus infections — but formulating the sprays is a challenge.
- Max Kozlov
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Nature Podcast |
Racism in Health: the harms of biased medicine
In this podcast special we explore the myriad ways people have injected biases and racism into modern medicine.
- Nick Petrić Howe
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Outlook |
Disinfecting the air with far-ultraviolet light
Devices that use wavelengths of sanitizing ultraviolet light that are safe for people could become a more common sight.
- Eric Bender
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Outlook |
Preparing health-care systems for future pandemics
Increased vigilance in hospitals, better data sharing and training drills can help ready the world to respond to infectious-disease outbreaks.
- Kristina Campbell
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Outlook |
Leaders can choose to prevent pandemics
Heads of state, prime ministers and presidents have the power to guard against inevitable future pandemics.
- Joanne Liu
- , Helen Clark
- & Michel Kazatchkine
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Career Column |
Four evidence-backed reasons to say ‘no’ to early-morning meetings
Everyone hates them and they’re rarely essential, say Adaira Landry and Resa E. Lewiss. So why are we still getting the calendar invites?
- Adaira Landry
- & Resa E. Lewiss
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Outlook |
Five ways to prepare for the next pandemic
COVID-19 and other infectious-disease outbreaks can teach us how to respond to future threats.
- Devi Sridhar
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Outlook |
Could an algorithm predict the next pandemic?
Machine learning could help to identify the viruses most likely to spill over from animals to people and cause future pandemics.
- Simon Makin
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Outlook |
Why climate change matters for pandemic preparedness
Computational ecologist Xavier Rodó explains how climate modelling might be used to offer an early warning of future disease outbreaks.
- Laura Vargas-Parada
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Outlook |
Mastering the art of persuasion during a pandemic
Health policymakers need to cultivate social trust and plan effective communication strategies well before the next infectious disease goes global.
- Elizabeth Svoboda
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Outlook |
How to eradicate the next pandemic disease
The elimination of smallpox from every region of the world took a huge effort. Getting rid of other infectious diseases, such as COVID-19, will be even more difficult.
- Sam Jones
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News |
How monkeypox is spreading, and more — this week’s best science graphics
Three enlightening science charts, selected by Nature editors.
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News & Views Forum |
Skin colour affects the accuracy of medical oxygen sensors
COVID-19 broadened the use of pulse oximeters for rapid blood-oxygen readings, but it also highlighted the fact that skin pigmentation alters measurements. Two groups of researchers analyse this issue, and its effects on people with dark skin.
- Matthew D. Keller
- , Brandon Harrison-Smith
- & Mohammed Shahriar Arefin
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News |
Omicron boosters could arm you against variants that don’t yet exist
Worries that the immune system would get ‘stuck’ on the original SARS-CoV-2 strain are dispelled by laboratory experiments.
- Sara Reardon
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Nature Video |
Exoskeleton boots could power your walk by learning your stride
New design uses model based on lab data to adapt for wearers while in use.
- Dan Fox
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News Feature |
What does the future look like for monkeypox?
With cases declining in the United States and Europe, Nature examines scenarios of how the outbreak might play out.
- Sara Reardon
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Editorial |
Studies linking diet with health must get a whole lot better
A research-rating system has identified gaps in studies that assess the connection between diet and various health risks.
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News Feature |
COVID jabs for kids: they’re safe and they work — so why is uptake so patchy?
Some countries are now offering COVID vaccines for children as young as six months. Nature looks at how effective they are and why more kids haven’t had them.
- Smriti Mallapaty