Nature

Constipation

Constipation describes infrequent bowel movements (three times a week or less according to the Rome III criteria), or those that are hard to pass. Constipation is a symptom that has a range of causes, including low levels of fibre or liquid in the diet, certain medications and structural abnormalities.

Latest Research and Reviews

Research
15 August 2022 | Open Access

Impact of habitual chewing on gut motility via microbiota transition
- Fukie Yaoita
- , Keita Watanabe
- & Koichi Tan-No
Scientific Reports 12, 13819
Reviews
22 April 2022 | Open Access

Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s disease
- Alcmène Chalazonitis
- , Meenakshi Rao
- & David Sulzer
npj Parkinson's Disease 8, 50
Research
19 January 2022 | Open Access

Excessive laxity of connective tissue in constipated children
- Andrzej Załęski
- , Agnieszka Gawrońska
- & Marcin Banasiuk
Scientific Reports 12, 1026
Research | 23 April 2021

The Malone antegrade continence enema adapting a transanal irrigation system in patients with neurogenic bowel dysfunction
- Michele Spinelli
- , Gianluca Sampogna
- & Osvaldo Chiara
Spinal Cord Series and Cases 7, 34
Research
27 January 2021 | Open Access

Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
- Kazunori Matsuda
- , Takuya Akiyama
- & Junji Fujimoto
Scientific Reports 11, 2400
Research
04 November 2020 | Open Access

Constipation and sleep behaviour disorder associate with processing speed and attention in males with Parkinson’s disease over five years follow-up
- Wee Lee Kong
- , Yue Huang
- & Margaret J. Morris
Scientific Reports 10, 19014

All Research & Reviews

News and Comment

News & Views | 18 November 2015

Colectomy for constipation—a time for renewed caution?

Colectomy is rightly viewed as a last resort in selected patients with slow-transit constipation. A new study presents US national data that raises new concerns regarding the outcome of this procedure and perhaps questions whether it should be offered at all.
- Charles H. Knowles
Nature Reviews Gastroenterology & Hepatology 12, 675-676
Research Highlights | 01 July 2014

CO₂-releasing suppository quickly and effectively relieves constipation
- Claire Greenhill
Nature Reviews Gastroenterology & Hepatology 11, 455
Research Highlights | 02 October 2012

Linaclotide approved for constipation-predominant IBS
- Katrina Ray
Nature Reviews Gastroenterology & Hepatology 9, 616
Research Highlights | 11 September 2012

Colonic manometry helps children who deny sensation to defecate
- Claire Greenhill
Nature Reviews Gastroenterology & Hepatology 9, 560
Research Highlights | 14 February 2012

Searching for 5-HT₄ receptors in the colonic mucosa
- Katrina Ray
Nature Reviews Gastroenterology & Hepatology 9, 125
Research Highlights | 27 December 2011

Treat constipation before measuring PSA levels

Nature Reviews Urology 9, 5

All News & Comment

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