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| Open AccessSwitch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX
- Yang Hu
- , Guang Shi
- & Junjiu Huang
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| Open AccessA Nomogram for Predicting the Pathological Response of Axillary Lymph Node Metastasis in Breast Cancer Patients
- Xi Jin
- , Yi-Zhou Jiang
- & Gen-Hong Di
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| Open AccessDoxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice
- Jayanth Suryanarayanan Shankaranarayanan
- , Jagat R. Kanwar
- & Rupinder K. Kanwar
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| Open AccessUltra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams
- S. Raschke
- , S. Spickermann
- & F. Boege
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| Open AccessForced co-expression of IL-21 and IL-7 in whole-cell cancer vaccines promotes antitumor immunity
- Yang-Zhuo Gu
- , Chuan-Wen Fan
- & Yu-Quan Wei
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| Open AccessEF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma
- Da-long Yin
- , Ying-jian Liang
- & Lian-xin Liu
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| Open AccessYu Ping Feng San reverses cisplatin-induced multi-drug resistance in lung cancer cells via regulating drug transporters and p62/TRAF6 signalling
- Jian-Shu Lou
- , Lu Yan
- & Karl W. K. Tsim
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| Open AccessDown-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions
- Song Yi Bae
- , Hyen Joo Park
- & Sang Kook Lee
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Article
| Open AccessCombined expression of miR-34a and Smac mediated by oncolytic vaccinia virus synergistically promote anti-tumor effects in Multiple Myeloma
- Wen Lei
- , Shibing Wang
- & Wenbin Qian
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| Open AccessMonitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab
- Chiara Nicolazzo
- , Cristina Raimondi
- & Paola Gazzaniga
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| Open AccessCirculating Tumour Cells as an Independent Prognostic Factor in Patients with Advanced Oesophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy
- Po-Jung Su
- , Min-Hsien Wu
- & Chia-Hsun Hsieh
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| Open AccessThe association of medication-related osteonecrosis of the jaw with Actinomyces spp. infection
- Guenter Russmueller
- , Rudolf Seemann
- & Christoph Steininger
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| Open AccessStructurally novel steroidal spirooxindole by241 potently inhibits tumor growth mainly through ROS-mediated mechanisms
- Xiao-Jing Shi
- , Bin Yu
- & Hong-Min Liu
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Article
| Open AccessElimination of microglia improves cognitive function following cranial irradiation
- Munjal M. Acharya
- , Kim N. Green
- & Charles L. Limoli
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Article
| Open AccessA Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor Activity
- Yan-Bo Zheng
- , Jian-Hua Gong
- & Yong-Su Zhen
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| Open AccessNormal tissue radioprotection by amifostine via Warburg-type effects
- Michael I. Koukourakis
- , Alexandra Giatromanolaki
- & Adrian L. Harris
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Article
| Open AccessHuaier restrains proliferative and invasive potential of human hepatoma SKHEP-1 cells partially through decreased Lamin B1 and elevated NOV
- Zhongdong Hu
- , Ailin Yang
- & Pengfei Tu
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Article
| Open AccessVorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells
- Vivek Nandakumar
- , Nanna Hansen
- & Deirdre R. Meldrum
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Article
| Open AccessPKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer
- Haiyan Zhu
- , Jun Wu
- & Xueqiong Zhu
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Article
| Open AccessUltrasensitive sandwich-type electrochemical immunosensor based on trimetallic nanocomposite signal amplification strategy for the ultrasensitive detection of CEA
- Lihui Tian
- , Li Liu
- & Wei Cao
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Article
| Open AccessMetformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC
- Hongxin Cao
- , Wei Dong
- & Jiajun Du
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| Open AccessTuning the anticancer activity of a novel pro-apoptotic peptide using gold nanoparticle platforms
- Mohammad Akrami
- , Saeed Balalaie
- & Ismaeil Haririan
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Article
| Open AccessArsenite-loaded nanoparticles inhibit PARP-1 to overcome multidrug resistance in hepatocellular carcinoma cells
- Hanyu Liu
- , Zongjun Zhang
- & Jinhao Gao
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Article
| Open AccessCell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo
- Keisuke Otani
- , Yoko Naito
- & Masaru Ishii
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Article
| Open AccessImatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy
- Yuko Tsutsui
- , Daniel Deredge
- & Franklin A. Hays
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Article
| Open AccessInactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells
- Tian-yi Zhou
- , Lin-han Zhuang
- & Bo Yang
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| Open AccessFolate-Chitosan Nanoparticles Loaded with Ursolic Acid Confer Anti-Breast Cancer Activities in vitro and in vivo
- Hua Jin
- , Jiang Pi
- & Zheng W. Chen
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| Open AccessNovel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells
- Mohieldin M. Youssef
- , Mai F. Tolba
- & Ashraf B. Abdel-Naim
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| Open AccessC-terminal domain of p42 Ebp1 is essential for down regulation of p85 subunit of PI3K, inhibiting tumor growth
- Inwoo Hwang
- , Chung Kwon Kim
- & Jee-Yin Ahn
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| Open AccessCo-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer
- Hong Yan Liu
- , Xiaolin Yu
- & Jin-Xiong She
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| Open AccessPancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems
- Mei-Ju Su
- , Hibah Aldawsari
- & Mansoor Amiji
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| Open AccessNeurogenic differentiation factor NeuroD confers protection against radiation-induced intestinal injury in mice
- Ming Li
- , Aonan Du
- & Jianping Cao
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| Open AccessPhenotypically distinct helper NK cells are required for gp96-mediated anti-tumor immunity
- Abigail L. Sedlacek
- , Lauren B. Kinner-Bibeau
- & Robert J. Binder
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Article
| Open AccessCardiac glycosides display selective efficacy for STK11 mutant lung cancer
- Nayoung Kim
- , Hwa Young Yim
- & Sukjoon Yoon
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| Open AccessOxidative stress-mediated intrinsic apoptosis in human promyelocytic leukemia HL-60 cells induced by organic arsenicals
- Xiao-Yang Fan
- , Xin-You Chen
- & Yi Liu
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Article
| Open AccessChloroquine enhanced the anticancer capacity of VNP20009 by inhibiting autophagy
- Xiaoxin Zhang
- , Qiaoqiao Xu
- & Zichun Hua
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| Open AccessOver-expression of DNA-PKcs in renal cell carcinoma regulates mTORC2 activation, HIF-2α expression and cell proliferation
- Bing Zheng
- , Jia-Hui Mao
- & Xiao-dong Pan
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Article
| Open AccessOncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents
- David Perera
- & Ashok R. Venkitaraman
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Article
| Open AccessMultimodal Imaging of Nanocomposite Microspheres for Transcatheter Intra-Arterial Drug Delivery to Liver Tumors
- Dong-Hyun Kim
- , Weiguo Li
- & Andrew C. Larson
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| Open AccessImpact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib
- Géraldine Dessilly
- , Nadtha Panin
- & Jean-Baptiste Demoulin
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| Open AccessLinifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer
- Jing Chen
- , Jiawei Guo
- & Xiufeng Pang
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Article
| Open AccessCathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors
- Chien-Chang Huang
- , Cheng-Che Lee
- & Jang-Yang Chang
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Article
| Open AccessMultiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity
- Zhenghu Chen
- , Zhenyu Wang
- & Jianhua Yang
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| Open AccessExpression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide
- Hai Wang
- , Wenfeng Feng
- & Yawei Liu
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| Open AccessSynergistic Effect of H2O2 and NO2 in Cell Death Induced by Cold Atmospheric He Plasma
- Pierre-Marie Girard
- , Atousa Arbabian
- & João Santos Sousa
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| Open AccessInhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors
- Hyeon-Ok Jin
- , Sung-Eun Hong
- & Jin Kyung Lee
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Article
| Open AccessBisdemethoxycurcumin inhibits ovarian cancer via reducing oxidative stress mediated MMPs expressions
- Haifeng Pei
- , Yi Yang
- & Haixia Duan
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Article
| Open AccessDownregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo
- Jiwen Wang
- , Yanli Yao
- & Houbao Liu
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| Open AccessIntramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains
- Ana Alvarez-Cienfuegos
- , Natalia Nuñez-Prado
- & Luis Alvarez-Vallina