Featured
-
-
Article
| Open Access
Preparation of orodispersible tablets of bosentan using xylitol and menthol as dissolution enhancers
- Rania Mohamed Sakr
- , Abdelaziz El Sayed Abdelaziz
- & Gamal Mohamed El Maghraby
-
Article
| Open Access
Development of a new affinity maturation protocol for the construction of an internalizing anti-nucleolin antibody library
- Rita Ribeiro
- , João N. Moreira
- & João Goncalves
-
Article
| Open Access
Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (Mpro)
- Deepika Geedkar
- , Ashok Kumar
- & Pratibha Sharma
-
Article
| Open Access
Real life experience on the use of Remdesivir in patients admitted to COVID-19 in two referral Italian hospital: a propensity score matched analysis
- Nicola Veronese
- , Francesco Di Gennaro
- & Annalisa Saracino
-
Article
| Open Access
Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore
- Monica Cozzi
- , Mariacristina Failla
- & Francesca Spyrakis
-
Article
| Open Access
Lack of association between COVID-19 vaccines and miscarriage onset using a case-crossover design
- Irati Gastesi Orbegozo
- , Lucía Cea-Soriano
- & Consuelo Huerta-Álvarez
-
Article
| Open Access
Background and clinical significance of biomarker-based patient enrichment in non-small-cell lung cancer drug development
- Kenji Harada
- & Shunsuke Ono
-
Article
| Open Access
Fe3O4@Chitosan@ZIF-8@RVG29, an anti-glioma nanoplatform guided by fixed and activated by alternating magnetic field
- Mohammad-Nabil Savari
-
Article
| Open Access
Transfection of hypoxia-inducible factor-1α mRNA upregulates the expression of genes encoding angiogenic growth factors
- Jakub Wlodarczyk
- , Albert Leng
- & John W. Harmon
-
Article
| Open Access
Nortriptyline hydrochloride, a potential candidate for drug repurposing, inhibits gastric cancer by inducing oxidative stress by triggering the Keap1-Nrf2 pathway
- Chunyang Zhu
- , Yangyang Lu
- & Weiwei Qi
-
Article
| Open Access
Apomorphine is a potent inhibitor of ferroptosis independent of dopaminergic receptors
- Akihiko Miyauchi
- , Chika Watanabe
- & Hitoshi Osaka
-
Article
| Open Access
Pacritinib inhibits proliferation of primary effusion lymphoma cells and production of viral interleukin-6 induced cytokines
- Yiquan Wu
- , Victoria Wang
- & Robert Yarchoan
-
Article
| Open Access
Quercetin-crosslinked chitosan nanoparticles: a potential treatment for allergic rhinitis
- Dehong Mu
- , Li Zhou
- & Li Tian
-
Article
| Open Access
A pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration
- Anna L. Beukenhorst
- , Jacopo Frallicciardi
- & Jaap Goudsmit
-
Article
| Open Access
Evaluation of the antidermatophytic activity of potassium salts of N-acylhydrazinecarbodithioates and their aminotriazole-thione derivatives
- Anita Ciesielska
- , Aleksandra Kowalczyk
- & Paweł Stączek
-
Article
| Open Access
Crystallization kinetics of nanoconfined GeTe slabs in GeTe/TiTe\(_2\)-like superlattices for phase change memories
- Debdipto Acharya
- , Omar Abou El Kheir
- & Marco Bernasconi
-
Article
| Open Access
Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry
- Xueyuan Guo
- , Juan Du
- & Jian Zhang
-
Article
| Open Access
Factors influencing pain medication and opioid use in patients with musculoskeletal injuries: a retrospective insurance claims database study
- Stefan Markus Scholz
- , Nicolas Fabrice Thalmann
- & Maria Monika Wertli
-
Article
| Open Access
Evaluation of a simplified pharmacovigilance tool for general practitioners: 5 years of insight
- A. Trenque
- , A. Rabiaza
- & X. Humbert
-
Article
| Open Access
Revealing the mechanistic interactions of profenofos and captan pesticides with serum protein via biophysical and computational investigations
- Kamonrat Phopin
- , Waralee Ruankham
- & Tanawut Tantimongcolwat
-
Article
| Open Access
A comparative study of clinical trial and real-world data in patients with diabetic kidney disease
- Samu Kurki
- , Viivi Halla-aho
- & Miika Koskinen
-
Article
| Open Access
A systematic review and network meta-analysis of pharmaceutical interventions used to manage chronic pain
- Ashish Shetty
- , Gayathri Delanerolle
- & Jian Qing Shi
-
Article
| Open Access
Dynamics of technology emergence in innovation networks
- Martin Ho
- , Henry C. W. Price
- & Eoin O’Sullivan
-
Article
| Open Access
Meldrum’s acid assisted formation of tetrahydroquinolin-2-one derivatives a short synthetic pathway to the biologically useful scaffold
- Małgorzata Ryczkowska
- , Alicja Trocka
- & Sławomir Makowiec
-
Article
| Open Access
PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo
- Elizabeth J. Brown
- , Leire Balaguer-Lluna
- & Gillian Farnie
-
Article
| Open Access
The thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models
- J. Joubert
- , S. M. Meiring
- & W. J. Janse van Rensburg
-
Article
| Open Access
Myricetin suppresses traumatic brain injury-induced inflammatory response via EGFR/AKT/STAT pathway
- Chenxing Wang
- , Siguang Ouyang
- & Peipei Gong
-
Article
| Open Access
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
- Barbara Cellini
- , Gioena Pampalone
- & Claudio Costantini
-
Article
| Open Access
KTt-45, a T-type calcium channel blocker, acts as an anticancer agent by inducing apoptosis on HeLa cervical cancer cell line
- Nguyen Huy Du
- , Truong Thi Bich Ngoc
- & Dang Thi Phuong Thao
-
Article
| Open Access
Calcium phosphate ceramics combined with rhBMP6 within autologous blood coagulum promote posterolateral lumbar fusion in sheep
- Natalia Ivanjko
- , Nikola Stokovic
- & Slobodan Vukicevic
-
Article
| Open Access
Influence of pneumatic transportation on the stability of monoclonal antibodies
- Pierre Coliat
- , Stéphane Erb
- & Xavier Pivot
-
Article
| Open Access
A Notch signaling-related lncRNA signature for predicting prognosis and therapeutic response in clear cell renal cell carcinoma
- Lulu Zhang
- , Yulei Li
- & Ke Zhu
-
Article
| Open Access
Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy
- A. C. L. Mortensen
- , H. Berglund
- & M. Nestor
-
Article
| Open Access
The combination of Ephedrae herba and coixol from Coicis semen attenuate adiposity via glucocorticoid receptor regulation
- Ga-Ram Yu
- , Jai-Eun Kim
- & Won-Hwan Park
-
Article
| Open AccessSociodemographic characteristics of healthy volunteers along with their experience, attitude and concerns of clinical trials in Wuhan, China
- Hengyi Yu
- , Yinian Fang
- & Xiuhua Ren
-
Article
| Open Access
Antifibrotic effect of apremilast in systemic sclerosis dermal fibroblasts and bleomycin-induced mouse model
- Tomoaki Higuchi
- , Kae Takagi
- & Yasushi Kawaguchi
-
Article
| Open Access
9-oxo-ODAs suppresses the proliferation of human cervical cancer cells through the inhibition of CDKs and HPV oncoproteins
- Kazumasa Mogi
- , Yoshihiro Koya
- & Hiroaki Kajiyama
-
Article
| Open Access
Efficacy and safety of polyethylene glycol loxenatide in type 2 diabetic patients: a systematic review and meta-analysis of randomized controlled trials
- Hazem Mohamed Salamah
- , Ahmed Marey
- & Mohamed Abd-Elgawad
-
Article
| Open Access
Efficacy and safety of eltrombopag in Chinese patients with refractory or relapsed severe aplastic anemia
- Hong Chang
- , Guangsheng He
- & Fengkui Zhang
-
Article
| Open Access
The synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression
- Manman Deng
- , Jinshui Tan
- & Bing Xu
-
Article
| Open Access
The quality monitoring of paracetamol medicament using a noninvasive microwave sensor
- Youness Zaarour
- , Fatimazahrae EL Arroud
- & M’hamed Drissi
-
Article
| Open Access
Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19
- Rob C. van Wijk
- , Laurynas Mockeliunas
- & Ulrika S. H. Simonsson
-
Article
| Open Access
Large numbers of patients are needed to obtain additional approvals for new cancer drugs: A retrospective cohort study
- Charlotte Ouimet
- , Nora Hutchinson
- & Jonathan Kimmelman
-
Article
| Open Access
A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment
- Cheng-Hsin Wei
- , Lu Huang
- & Xi Liu
-
Article
| Open Access
Genomic and transcriptomic analysis of camptothecin producing novel fungal endophyte: Alternaria burnsii NCIM 1409
- Shakunthala Natarajan
- , Boas Pucker
- & Smita Srivastava
-
Article
| Open Access
Identification of potential new COVID-19 treatments via RWD-driven drug repurposing
- Yun Liao
-
Article
| Open Access
Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer
- Hamid Jamialahmadi
- , Seyedeh Elnaz Nazari
- & Amir Avan
-
Article
| Open Access
Green “turn-off” luminescent nanosensors for the sensitive determination of desperately fluorescent antibacterial antiviral agent and its metabolite in various matrices
- Hadil M. Elbardisy
- , Mai M. Elnaggar
- & Amira F. El-Yazbi
-
Article
| Open Access
Experimental solubility of aripiprazole in supercritical carbon dioxide and modeling
- Eslam Ansari
- , Bizhan Honarvar
- & Mehdi Azizi
A novel anti-LAG-3/TIGIT bispecific antibody exhibits potent anti-tumor efficacy in mouse models as monotherapy or in combination with PD-1 antibody