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ITGB1 and DDR activation as novel mediators in acquired resistance to osimertinib and MEK inhibitors in EGFR-mutant NSCLC
- Caterina De Rosa
- , Viviana De Rosa
- & Carminia Maria Della Corte
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Targeted inhibition of the ATR/CHK1 pathway overcomes resistance to olaparib and dysregulates DNA damage response protein expression in BRCA2MUT ovarian cancer cells
- Łukasz Biegała
- , Arkadiusz Gajek
- & Aneta Rogalska
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Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
- Tina Pekeč
- , Saradha Venkatachalapathy
- & G. V. Shivashankar
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Effective clearance of rituximab-resistant tumor cells by breaking the mirror-symmetry of immunoglobulin G and simultaneous binding to CD55 and CD20
- Sang Min Lee
- , Sung-Won Min
- & Sang Taek Jung
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Observational study of surgical resection in small non-functional pancreatic neuroendocrine tumors: AS SEER-based study
- Jiajing Lin
- & Heguang Huang
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IL-1β is involved in docetaxel chemoresistance by regulating the formation of polyploid giant cancer cells in non-small cell lung cancer
- Song Zhao
- , Sining Xing
- & Huiying Yu
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DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost
- Taixiang Wang
- , Alastair H. Kyle
- & Andrew I. Minchinton
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Bone scan index (BSI) scoring by using bone scintigraphy and circulating tumor cells (CTCs): predictive factors for enzalutamide effectiveness in patients with castration-resistant prostate cancer and bone metastases
- Hisashi Hirano
- , Masayoshi Nagata
- & Shigeo Horie
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NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells
- Umit Aliyaskarova
- , Yeldar Baiken
- & Regina Groisman
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The cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma
- Lenka Besse
- , Marianne Kraus
- & Ignazio Tarantino
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Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer
- Narmeen S. Rashid
- , David C. Boyd
- & J. Chuck Harrell
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Ponatinib sensitizes myeloma cells to MEK inhibition in the high-risk VQ model
- Evan Flietner
- , Zhi Wen
- & Jing Zhang
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Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients
- Kaori Yoriki
- , Taisuke Mori
- & Jo Kitawaki
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Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse
- Simona Dalin
- , Beatrice Grauman-Boss
- & Michael T. Hemann
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Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance
- Anyue Yin
- , Johan G. C. van Hasselt
- & Dirk Jan A. R. Moes
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AKR1C1/2 inhibition by MPA sensitizes platinum resistant ovarian cancer towards carboplatin
- Susann Badmann
- , Doris Mayr
- & Bastian Czogalla
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Mutated RAS-associating proteins and ERK activation in relapse/refractory diffuse large B cell lymphoma
- Alexandre Benoit
- , Elisabeth Bou-Petit
- & Koren K. Mann
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Enhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens
- Ditte E. Jæhger
- , Mie L. Hübbe
- & Thomas L. Andresen
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Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers
- Martina Meßner
- , Melanie M. Mandl
- & Johanna Pachmayr
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Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin
- Michele Lai
- , Rachele Amato
- & Mauro Pistello
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Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p
- Roberto H. Barbier
- , Edel M. McCrea
- & William D. Figg
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A novel synthetic microtubule inhibitor exerts antiproliferative effects in multidrug resistant cancer cells and cancer stem cells
- Mina Park
- , Jee Won Hwang
- & Yong Kee Kim
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Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma
- Jacob W. Greenberg
- , Hogyoung Kim
- & Louis S. Krane
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Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients
- Mohamed A. Ismail
- , Marzia Vezzalini
- & Nader I. Al-Dewik
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PIM kinases mediate resistance to cisplatin chemotherapy in hepatoblastoma
- Raoud Marayati
- , Laura L. Stafman
- & Elizabeth A. Beierle
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Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study
- Rebekah L. I. Crake
- , Matthew R. Strother
- & Margaret J. Currie
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The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers
- Stijn Moens
- , Peihua Zhao
- & Frédéric Amant
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Depletion of Survivin suppresses docetaxel-induced apoptosis in HeLa cells by facilitating mitotic slippage
- Teng-Long Han
- , Hang Sha
- & Zhi-Xin Jiang
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Electronic cigarette aerosols alter the expression of cisplatin transporters and increase drug resistance in oral cancer cells
- Jimmy Manyanga
- , Vengatesh Ganapathy
- & Lurdes Queimado
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Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer
- Ryoichi Katsube
- , Kazuhiro Noma
- & Toshiyoshi Fujiwara
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Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells
- Nobuki Matsumoto
- , Miku Ebihara
- & Toru Imamura
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Targeting mTOR and DNA repair pathways in residual triple negative breast cancer post neoadjuvant chemotherapy
- Kartik Anand
- , Tejal Patel
- & Jenny Chang
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Anti-tumour activity of deer growing antlers and its potential applications in the treatment of malignant gliomas
- Louis Chonco
- , Tomás Landete-Castillejos
- & Tomás Segura
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Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer
- Ryota Takahashi
- , Hideaki Ijichi
- & Kazuhiko Koike
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Autologous culture method improves retention of tumors’ native properties
- Yao Tang
- , Qian Xu
- & Jiang Gu
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Identification of synthetic chemosensitivity genes paired with BRAF for BRAF/MAPK inhibitors
- Kye Hwa Lee
- , Jinmin Goh
- & Kwangsoo Kim
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Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based cultures
- Sofia Abreu
- , Fernanda Silva
- & Catarina Brito
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Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer
- Lung-Hung Tsai
- , Kai-Wen Hsu
- & Heng-Hsiung Wu
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Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma
- Zammam Areeb
- , Sarah F. Stuart
- & Rodney B. Luwor
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Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells
- Agnese Po
- , Anna Citarella
- & Elisabetta Ferretti
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EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells
- Seiko Yoshino
- , Yusuke Matsui
- & Takeharu Sakamoto
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A novel anti-HER2 antibody GB235 reverses Trastuzumab resistance in HER2-expressing tumor cells in vitro and in vivo
- Mengjun Shu
- , Hongbin Yan
- & Joe X. Zhou
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Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy
- Kenji Ichikawa
- , Saori Watanabe Miyano
- & Yasuhiro Funahashi
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Screening of potential miRNA therapeutics for the prevention of multi-drug resistance in cancer cells
- Zdravka Medarova
- , Pamela Pantazopoulos
- & Byunghee Yoo
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BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis
- Jasdeep Mann
- , Ning Yang
- & Ing Swie Goping
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Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma
- Nancy S. Younis
- , Amal M. H. Ghanim
- & Sameh Saber
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Article
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MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia
- María Luz Morales
- , Alicia Arenas
- & Joaquín Martínez-López
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Article
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The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells
- Matheus Molina Silva
- , Clarissa Ribeiro Reily Rocha
- & Carlos Frederico Martins Menck
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Sema4C mediates EMT inducing chemotherapeutic resistance of miR-31-3p in cervical cancer cells
- Li Jing
- , Wang Bo
- & Wu Mingfu
An inflamed tumor cell subpopulation promotes chemotherapy resistance in triple negative breast cancer