Outlook |
Featured
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Outlook |
Adoptive cell therapy: Honing that killer instinct
Genetically altered immune cells are helping to push life-threatening cancers into remission and generating a buzz.
- Courtney Humphries
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Outlook |
Drug development: Releasing the brakes
Tumours can put a brake on the immune system, but new therapies work by removing these brakes. Now, researchers have to figure out how to use them most effectively.
- Karen Weintraub
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Outlook |
Perspective: Assembly line immunotherapy
Bruce L. Levine and Carl H. June explore how to make engineered immune cells that can eradicate cancer widely available.
- Bruce L. Levine
- & Carl H. June
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News & Views |
Tumours switch to resist
Tumour cells can respond to targeted immune-cell therapies by losing proteins that mark them as being cancerous. Subverting this resistance mechanism may lead to more durable cancer-treatment strategies. See Letter p.412
- Antoni Ribas
- & Paul C. Tumeh
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News |
Antibody alarm call rouses immune response to cancer
Trial drug outperforms earlier efforts to marshall the body’s defences to combat tumours.
- Erika Check Hayden
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Review Article |
Cancer immunotherapy comes of age
An overview of the latest advances in cancer immunotherapy.
- Ira Mellman
- , George Coukos
- & Glenn Dranoff
Medical imaging: Removing the blindfold