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| Open AccessEffects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats
- Camila Tami Stringhetta-Garcia
- , Samuel Rodrigues Lourenço Morais
- & Rita Cássia Menegati Dornelles
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| Open AccessFace-specific memory deficits and changes in eye scanning patterns among patients with amnestic mild cognitive impairment
- Toshikazu Kawagoe
- , Masateru Matsushita
- & Kaoru Sekiyama
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| Open AccessThe contribution of Saccharomyces cerevisiae replicative age to the variations in the levels of Trx2p, Pdr5p, Can1p and Idh isoforms
- Aglaia V. Azbarova
- , Kseniia V. Galkina
- & Dmitry A. Knorre
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| Open AccessHow to prevent the detrimental effects of two months of bed-rest on muscle, bone and cardiovascular system: an RCT
- Andreas Kramer
- , Albert Gollhofer
- & Markus Gruber
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| Open AccessIL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
- Mary F. O’Leary
- , Graham R. Wallace
- & Simon W. Jones
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| Open AccessTransient postnatal overfeeding causes liver stress-induced premature senescence in adult mice
- Catherine Yzydorczyk
- , Na Li
- & Umberto Simeoni
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| Open AccessAnserine (beta-alanyl-3-methyl-L-histidine) improves neurovascular-unit dysfunction and spatial memory in aged AβPPswe/PSEN1dE9 Alzheimer’s-model mice
- Jun Kaneko
- , Akiko Enya
- & Tatsuhiro Hisatsune
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| Open AccessThe effect of sleep restriction on empathy for pain: An fMRI study in younger and older adults
- Sandra Tamm
- , Gustav Nilsonne
- & Mats Lekander
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| Open AccessEstrogenic vascular effects are diminished by chronological aging
- Christopher J. Nicholson
- , Michèle Sweeney
- & Michael J. Taggart
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| Open AccessLocal Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila
- M. M. Rahman
- , X. Franch-Marro
- & A. Casali
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| Open AccessMatrisome Profiling During Intervertebral Disc Development And Ageing
- Joana Caldeira
- , Cátia Santa
- & Mário Barbosa
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| Open AccessThe effects of ageing and adrenergic challenge on electrocardiographic phenotypes in a murine model of long QT syndrome type 3
- Karan R. Chadda
- , Shiraz Ahmad
- & Kamalan Jeevaratnam
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| Open Access5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- Tzu-Ching Chang
- , Min-Fen Hsu
- & Kenneth K. Wu
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| Open AccessDevelopment of new experimental platform ‘MARS’—Multiple Artificial-gravity Research System—to elucidate the impacts of micro/partial gravity on mice
- Dai Shiba
- , Hiroyasu Mizuno
- & Satoru Takahashi
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| Open AccessSex-Specific Routes To Immune Senescence In Drosophila melanogaster
- Marco Kubiak
- & Matthew C. Tinsley
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| Open AccessAntibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer’s disease
- Myles R. Minter
- , Reinhard Hinterleitner
- & Sangram S. Sisodia
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| Open AccessDifferential changes in the adenoids and tonsils in Japanese children and teenagers: a cross-sectional study
- Asuka Manabe
- , Takayoshi Ishida
- & Takashi Ono
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| Open AccessPlacental Dysfunction Underlies Increased Risk of Fetal Growth Restriction and Stillbirth in Advanced Maternal Age Women
- Samantha C. Lean
- , Alexander E. P. Heazell
- & Rebecca L. Jones
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| Open AccessCalorie restriction effects on circadian rhythms in gene expression are sex dependent
- Artem A. Astafev
- , Sonal A. Patel
- & Roman V. Kondratov
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| Open AccessExposure to Violence Accelerates Epigenetic Aging in Children
- Tanja Jovanovic
- , L. Alexander Vance
- & Alicia K. Smith
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| Open AccessAmalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy
- Vikas Kumar
- , kumar A. Aneesh
- & C. C Kartha
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| Open AccessResistance training regulates gene expression of molecules associated with intramyocellular lipids, glucose signaling and fiber size in old rats
- Manoel Benício Teixeira Ribeiro
- , Vinicius Guzzoni
- & João Luiz Q. Durigan
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| Open AccessA time-varying biased random walk approach to human growth
- Béla Suki
- & Urs Frey
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| Open AccessDifferential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
- Virginie Gabel
- , Carolin F. Reichert
- & Antoine U. Viola
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| Open AccessThe Transcription Factor DAF-16 is Essential for Increased Longevity in C. elegans Exposed to Bifidobacterium longum BB68
- Liang Zhao
- , Yang Zhao
- & Fazheng Ren
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| Open AccessMechanism of biofilm-mediated stress resistance and lifespan extension in C. elegans
- Olga Smolentseva
- , Ivan Gusarov
- & Evgeny Nudler
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| Open AccessA simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans
- Ai Yamaguchi
- , Ritsuko Matsumura
- & Makoto Akashi
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| Open AccessMyricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α
- Hoe-Yune Jung
- , Dongyeop Lee
- & Kyong-Tai Kim
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| Open AccessIron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis
- Abitha Sukumaran
- , JuOae Chang
- & Jonghan Kim
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| Open AccessThe effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent
- Luisa Boldrin
- , Jacob A. Ross
- & Jennifer E. Morgan
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| Open AccessDifferential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegans
- Emmanouil Kyriakakis
- , Nikolaos Charmpilas
- & Nektarios Tavernarakis
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| Open AccessEfficient Characterization and Classification of Contrast Sensitivity Functions in Aging
- Fang-Fang Yan
- , Fang Hou
- & Chang-Bing Huang
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| Open AccessThe production of fibroblast growth factor 23 is controlled by TGF-β2
- Martina Feger
- , Philipp Hase
- & Michael Föller
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| Open AccessResistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis
- Ashleigh M. Philp
- , Rebecca L. Collier
- & Simon W. Jones
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| Open AccessBooster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span
- Mauro Provinciali
- , Alessandra Barucca
- & Elisa Pierpaoli
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| Open AccessResveratrol Pretreatment Attenuates Concanavalin A-induced Hepatitis through Reverse of Aberration in the Immune Response and Regenerative Capacity in Aged Mice
- Tse-Hung Huang
- , Chin-Chang Chen
- & Sue-Heui Shieh
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| Open AccessReconstitution of ovarian function following transplantation of primordial germ cells
- Ming Zeng
- , Xiaoyan Sheng
- & Lin Liu
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| Open AccessA single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1
- Ju-Ling Liu
- , Callista Yee
- & Siegfried Hekimi
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| Open AccessFrom Lark to Owl: developmental changes in morningness-eveningness from new-borns to early adulthood
- Christoph Randler
- , Corina Faßl
- & Nadine Kalb
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| Open AccessGenome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens
- Meng Zhang
- , Feng-Bin Yan
- & Gui-Rong Sun
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| Open AccessOvine multiparity is associated with diminished vaginal muscularis, increased elastic fibres and vaginal wall weakness: implication for pelvic organ prolapse
- Stuart Emmerson
- , Natharnia Young
- & Caroline E. Gargett
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| Open AccessLifespan Gyrification Trajectories of Human Brain in Healthy Individuals and Patients with Major Psychiatric Disorders
- Bo Cao
- , Benson Mwangi
- & Jair C. Soares
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| Open AccessDynamic cortical participation during bilateral, cyclical ankle movements: effects of aging
- Takashi Yoshida
- , Kei Masani
- & Milos R. Popovic
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| Open AccessAtrial structure, function and arrhythmogenesis in aged and frail mice
- Hailey J. Jansen
- , Motahareh Moghtadaei
- & Robert A. Rose
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| Open AccessPupillary responses to short-wavelength light are preserved in aging
- A. V. Rukmini
- , Dan Milea
- & Joshua J. Gooley
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| Open AccessEffect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
- J. Fafián-Labora
- , I. Lesende-Rodriguez
- & M. C. Arufe
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| Open AccessA Frailty Index Based On Deficit Accumulation Quantifies Mortality Risk in Humans and in Mice
- K. Rockwood
- , J. M. Blodgett
- & S. E. Howlett
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| Open AccessModified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice
- Hikari Takeshita
- , Koichi Yamamoto
- & Hiromi Rakugi
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| Open AccessNew perspectives on corpora amylacea in the human brain
- Elisabet Augé
- , Itsaso Cabezón
- & Jordi Vilaplana