Acute pancreatitis articles within Nature Communications

Featured

• Article
  04 October 2023 | Open Access

  Gut microbiota aggravates neutrophil extracellular traps-induced pancreatic injury in hypertriglyceridemic pancreatitis

  Given the association of gut microbiota dysbiosis with hypertriglyceridemic pancreatitis (HTGP), authors assess the gut microbial diversity of patients with HTGP, and provide immunological insight utilising a murine model.

  • Guanqun Li
  • , Liwei Liu
  •  & Bei Sun

• Article
  28 November 2018 | Open Access

  A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation

  Inflammatory diseases of the pancreas are currently untreatable and lack a pre-clinical model that recapitulates the hallmarks of the human pathology. Here, the authors generate a knock-in mouse strain with increased tripsinogen autoactivation and show that it develops spontaneous pancreatic pathology with some key features of human pancreatitis.

  • Andrea Geisz
  •  & Miklós Sahin-Tóth