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Most localized prostate cancer can be cured with radiotherapy. Over the past decade, treatment courses have been shortened with no deterioration in cure rate or adverse effects. Now, a small phase II trial has tested whether radiation could be delivered as a single treatment.
Sperm analysis has a central role in diagnosing and treating male factor infertility. Emerging techniques have been developed that enable improved analysis of sperm motility, morphology and genetics to help overcome current limitations in accuracy and consistency, and improve sperm selection for infertility treatment.
In this Review the authors describe advances in our understanding of the molecular determinants of urinary tract infection pathogenesis, focusing on specific host susceptibility factors and their consequences.
Testosterone replacement therapy for the treatment of primary hypogonadism in men is associated with multiple adverse effects including infertility. The re-establishment of testosterone-producing cell lineages using stem-cell-based therapy has had promising results in pre-clinical studies and could be used in transplantation therapy.
