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Early use of salvage radiotherapy in patients with prostate cancer with biochemical recurrence after radical prostatectomy has consistently been shown to provide better oncological outcomes than late use. However, the corresponding scientific literature might be subject to lead-time bias, given that in virtually all the available comparative studies, investigators calculated the survival period of included patients from the time of salvage radiotherapy — instead of from the time of radical prostatectomy.
Health officials are warning that overuse of antibiotics and increasing antibiotic resistance mean that these drugs could soon become useless. Urologists have to take some responsibility as we continue to perform prostate biopsy sampling using a transrectal approach, which increases the possibility of bacterial infection.