Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In this Review, Siva and colleagues discuss the uses of (PSMA)–positron emission tomography (PET) beyond its role in conventional prostate cancer imaging. PSMA could have utility in other genitourinary malignancies and oligometastatic prostate cancer, theranostics, selection and guidance of radiotherapy fields, as well as the assessment of response to treatment.
The treatment paradigm for treatment-naive metastatic clear cell renal cell carcinoma continued to evolve in 2019 as three phase III randomized controlled trials were reported comparing sunitinib with combination immune checkpoint inhibitors and VEGF-targeted therapy. Pembrolizumab plus axitinib and avelumab plus axitinib became new treatment options for untreated patients, irrespective of risk group or PD-L1 expression.
In a recent study, Nobles et al. report that a substantial proportion of posts to an online forum on sexually transmitted infections were seeking diagnostic help. Forum users might perceive benefits to online crowd-based diagnosis, but this approach risks spreading harmful misinformation. More research is needed on crowd-based digital approaches to improve sexual health.
