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Spondyloarthritis

The eyes have it: uveitis in patients with spondyloarthritis

Although systemic lupus erythematosus is the prototype multisystem disease, many other inflammatory diseases are also promiscuous, with symptoms manifesting in many organs. Now, new data emphasize the extra-articular involvement in spondyloarthritis, predominantly affecting the eye; however, the factors that account for the observed organ involvement remain unknown.

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Figure 1: The skin, eyes, spine, peripheral joints, tendons and bowel can be simultaneously inflamed in spondyloarthritis.

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Acknowledgements

The authors are supported in part by NIH grant EY021733, Research to Prevent Blindness, the William and Mary Bauman Foundation, the Stan and Madelle Rosenfeld Family Trust, and the William C. Kuzell Foundation.

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Correspondence to James T. Rosenbaum.

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Rosenbaum, J., Rosenzweig, H. The eyes have it: uveitis in patients with spondyloarthritis. Nat Rev Rheumatol 8, 249–250 (2012). https://doi.org/10.1038/nrrheum.2012.43

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