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A growing body of epidemiological evidence linking air pollution to multiple brain disorders suggests that these adverse effects are produced by mechanisms that are shared across these disorders. More stringent, targeted regulatory policies may therefore be required to ensure public health protection.
In both human radiation-induced brain injury and a mouse model of this condition, activated microglia release chemokines that attract cytotoxic T cells from the periphery to the lesion site, and this exacerbates neuronal damage in the area.
The representational geometry of neural population activity in the somatosensory cortex of mice allows for high flexibility needed to perform complex tasks and for generalization to novel tasks at the same time.
Recent technological advances have provided insights into the diversity of neuronal subtypes within the midbrain dopamine system. In this Review, Garritsen and colleagues discuss molecular and functional distinctions between subtypes and describe mechanisms underlying their development, wiring and function.
Primates can quickly detect situations in which their performance deviates from the intended goal by the process of error monitoring. In this Review, Rutishauser and colleagues discuss the neuronal mechanisms that underlie such monitoring in macaques and humans.
In this Perspective article, Foster and colleagues describe converging evidence supporting an anatomical and functional division of the posterior cingulate cortex into three subregions that contribute to different cognitive tasks.
