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Scientific meetings are an opportunity to promote research and researchers. Anne-Marie M. Oswald and Srdjan Ostojic describe ways to promote diversity at the conference podium.
Progenitor cells in fetuses carrying Huntington disease-associated mutations show differences to controls, suggesting the disease may have a developmental component.
Strengthening of the developing retinogeniculate circuit in mouse pups is promoted by a neuronal receptor and locally restricted by the microglial release of the receptor’s ligand.
Juvenile social isolation in mice reduces a recruitment of medial prefrontal cortex (mPFC) to posterior paraventricular thalamus social behaviour circuit and thereby reduces sociability in adulthood.
Goal-directed primate behaviour is guided by abstract rules that group events and experiences into meaningful concepts. Here, Mansouri and colleagues discuss the distributed cortical and subcortical brain regions thought to underlie the formation, maintenance and implementation of abstract rules and propose a unified framework describing the neural architecture of rule-guided primate behaviour.
A resurgence in interest in the therapeutic potential of psychedelic drugs has boosted research into their neurobiological and cognitive effects. Vollenweider and Preller review recent advances in the field and consider the implications of recent discoveries for the therapeutic use of psychedelics.
Recent advances in animal addiction models have emphasized translational challenges. In this Review, Venniro and colleagues introduce a reverse translational approach that may provide an ecologically relevant platform from which to discover new circuits, test new medications and improve translation.
Major compelling questions about the functional role of the locus coeruleus nucleus that had been difficult to answer, given its remote location and diminutive size, have now become accessible via new neuroscience tools. In this Perspective, 14 investigators provide a historical context for recent discoveries and outline new vistas for investigation.