News & Comment

The level of CREB expression and activity predicts whether long-term memory will decline or improve with age after life-extending strategies.

Neuronal activity triggers the activation of thousands of enhancers and the synthesis of enhancer RNA.

Neuronal recordings in humans show mirror-like activity in the medial frontal and medial temporal cortices.

The enhanced neurogenesis that is triggered by the interaction of males with their offspring postpartum is important for father–offspring recognition.

The activation patterns of mitral cells may provide an early processing step in olfactory perception.

Chronic opioid exposure upregulates δ-opioid receptors, which can synergize with μ-opioid receptors in mediating analgesia.

CRF receptor 1 regulates anxiety-like behaviour by sensitizing 5-HT₂receptor signalling.

GABA_B receptors modulate multivesicular release and the Ca²⁺permeability of NMDA receptors at neuronal spines.

Modification of astrocytic Ca²⁺levels does not affect synaptic transmission in hippocampal slice preparations.

This issue contains a number of articles about neuron birth and development.

Leptin increases GluR1 expression and synaptic strength through inhibition of PTEN.

Noradrenergic innervation from the locus coeruleus stimulates recruitment of microglia to amyloid plaques and phagocytosis of amyloid-β peptides.