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  • A new 'bedside' method that detects effective connectivity can discriminate between the vegetative state and the minimally conscious state.

    • Leonie Welberg
    Research Highlight

  • Primed microglia are associated with accelerated decline in patients with neurodegenerative diseases, and a new study indicates that the dysregulation of certain proteins of the alternative complement pathway might trigger the priming process.

    • Sian Lewis
    Research Highlight

  • Two independent studies link mutant huntingtin to inactivation of the deacetylase enzyme SIRT1 and highlight a neuroprotective role for SIRT1 in mouse models of Huntington's disease.

    • Monica Hoyos Flight
    Research Highlight

  • The antidepressant fluoxetine increases synaptic plasticity in the amygdala and thereby facilitates fear erasure through extinction.

    • Leonie Welberg
    Research Highlight

  • Repetitive spontaneous activity in developing neural networks causes spatiotemporal clustering of functional synapses on dendrites.

    • Darran Yates
    Research Highlight

  • Two immune-related molecules regulate network rhythmicity by controlling GABA transmission.

    • Leonie Welberg
    Research Highlight

  • NEURL1A-mediated ubiquitylation of CPEB3 alters its activity and regulates hippocampal synaptic plasticity and memory formation.

    • Katherine Whalley
    Research Highlight