News & Comment

A study in male mice finds that neurons in the bed nucleus of the stria terminalis shape hypothalamic neural representations to control the transition from appetitive to consummatory innate social behaviour towards conspecifics of both sexes.

A new study shows that many olfactory sensory neurons in Aedes aegypti mosquitoes express more than one type of chemosensory receptor and some of these neurons can respond to multiple olfactory cues.

Combining high-throughput fluorescence-activated cell sorting and single-cell RNA sequencing, neurons with and without neurofibrillary tangles from people with Alzheimer disease were shown to have different molecular signatures.

Subtypes of pyramidal neurons influence the transcriptomic states of nearby microglia in the mouse somatosensory cortex.

Dynamin mediates vesicle scission during endocytosis, and here is shown to exist with syndapin 1 in biomolecular condensates at the endocytic zone that enable its participation in ultrafast endocytosis.

A study in mice finds that different dopamine neuron subsystems in the midbrain track food and fluid ingestion at different stages of this process, and that animals can use this information to learn about the results of ingestion.

Core features of the language network in the brain are consistent across languages and language families.

A subpopulation of GABAergic neurons in the mouse VTA drives restorative sleep in response to social defeat stress.

Dendritic arbors are shaped by adhesion-molecule interactions between developing dendrites and the extracellular environment that are transduced by dendritic mechanosensitive channels into local calcium transients.

Brain lesions in individuals who subsequently show remission of smoking addiction share a common connectivity profile.

A new study shows that α-synuclein can interact with protein components of membraneless organelles involved in mRNA metabolism, and that such interactions may have relevance in Parkinson disease.

A population of fever-generating neurons in the hypothalamus coordinates diverse sickness behaviours in mice.

In mice, infusions of young cerebrospinal fluid into the brains of aged animals promote oligodendrogenesis and improve memory.

A population of spinal interneurons that express prokineticin receptor 2 is needed in mice for the rewarding, antistress and prosocial effects of pleasant touch.

Neuronal activity in a key region of the mouse hypothalamus modulates adult hippocampal neurogenesis, promoting the formation of adult-born neurons that support cognition and affective function.

In rodents, absence seizures — a prominent manifestation of generalized epilepsy — drive activity-dependent myelination in the corpus callosum, increase interhemispheric synchrony and drive increases in seizure burden over time.

Mice show degradation of their hippocampal place code when they disengage from a virtual goal-directed navigation task.

Food craving-like behaviours in pregnant mice are associated with changes in dopamine signalling.

Two papers explore cortical contributions to the evaluation of social rank in mice.

Bright light exerts antinociceptive effects in mice by activating a visual circuit involving the periaqueductal grey.