News & Comment

A small population of neurons in the mouse brainstem coordinate sound production and volume control during vocalizations.

A study in mice helps to resolve a debate surrounding striatal DA dynamics and reward benefit or cost and also reveals motivation and transient striatal DA release have a bidirectional causal relationship.

In mice, specific pools of adult neural stem cells are recruited during pregnancy to support postpartum maternal behaviour.

Ongoing systemic and neurocognitive impairments that continue in a subset of individuals after infection with SARS-CoV-2 infection are found to be associated with reduced serotonin levels.

In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippocampus-dependent memory deficits.

A new biotinylation-based approach identifies previously unknown cell surface proteins of the axonal initial segment (AIS) and shows a role for contactin-1 in assembly of the AIS extracellular matrix.

Federica De Lazzari describes Arvid Carlsson’s 1957 paper, which provided evidence for the importance of dopamine in brain function.

The organization and diversity of neuronal and glial primary cilia and their connectivity in the human cortex is characterized in detail.

Fluorescent indicators can provide quantitative insights into the spatiotemporal dynamics of signalling molecules released by brain circuits. However, a mismatch between the experimental context and the experimental imaging settings often introduces unexpected errors and biases in such measurements. Appreciating this mismatch should help to arrive at unbiased estimates.

The macaque homologue of the dorsal medial prefrontal cortex tracks the reliability of social information and determines whether this information is used to guide choices during decision making.

Ketamine is ‘trapped’ in the pores of NMDA receptors in the lateral habenula, mediating sustained antidepressant effects in mice.

Grid cells develop in rats soon after they leave the nest. Here, Ulsaker-Janke et al. show that preventing exposure to straight boundaries from birth delays, but does not prevent, grid cell maturation in adult rats.

A new study shows that, in a numerical judgement task, individuals show differences in neuronal coding of numbers below and above approximately four in the medial temporal lobe.

Data sharing is an essential component of open science practice. The Brain Imaging Data Structure project has pioneered a way to organize neuroimaging and behavioural data that enables easy sharing and reuse. We present experiences from the BIDS project and highlight how standards can promote open science.

Following synaptic vesicle exocytosis, synaptotagmin 1 recruits a lipid signalling pathway within the presynaptic plasma membrane that drives local dynamin recruitment and membrane retrieval by endocytosis, thus maintaining membrane homeostasis.

In this Journal Club, Nathan Anthony Smith discusses a 2008 paper that documented a link between the noradrenergic modulatory network in the locus coeruleus and cortical astrocytes in vivo.

A study dissects the neural circuit through which pup cries induce oxytocin release and maternal behaviour in mice.

A study reports that in the mouse hippocampus, the induction of long-term potentiation is dependent on the structural functions of CaMKII and not its enzymatic activity.

A juvenile hormone-degrading enzyme localized in the insect equivalent of the blood–brain barrier governs which social role, forager or soldier, worker carpenter ants fulfil.

During retinal development in the mouse, angiogenesis was unexpectedly found to depend on temporally restricted dopamine production by retinal ganglion cells, rather than by canonical retinal dopamine neurons.