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Fluorescent indicators can provide quantitative insights into the spatiotemporal dynamics of signalling molecules released by brain circuits. However, a mismatch between the experimental context and the experimental imaging settings often introduces unexpected errors and biases in such measurements. Appreciating this mismatch should help to arrive at unbiased estimates.
Data sharing is an essential component of open science practice. The Brain Imaging Data Structure project has pioneered a way to organize neuroimaging and behavioural data that enables easy sharing and reuse. We present experiences from the BIDS project and highlight how standards can promote open science.
A growing body of epidemiological evidence linking air pollution to multiple brain disorders suggests that these adverse effects are produced by mechanisms that are shared across these disorders. More stringent, targeted regulatory policies may therefore be required to ensure public health protection.
