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Neuroscientific evidence is increasingly offered in court cases, with neuroscientists often acting as expert witnesses. Jones and colleagues discuss the important roles that neuroscientists serve, as well as the potential problems they, as well as judges and jurors, may encounter.
Recent studies have shown that the protein p11 (also known as S100A10) has an important role in depression-like behaviour and antidepressant actions. Greengard and colleagues discuss the molecular and cellular mechanisms that may underlie this role.
Two new studies in mice show that fibroblast growth factor 21 acts at the suprachiasmatic nucleus of the hypothalamus and the dorsal vagal complex of the hindbrain to regulate various adaptive responses to nutritional deprivation.
A new study shows that the switch of sonic hedgehog from an attractive to a repulsive signal for commissural axon navigation involves the heparan sulphate proteoglycan glypican 1 and induction of Hedgehog-interacting protein expression.
Neural insults in conditions such as multiple sclerosis induce changes in the brain's extracellular matrix (ECM) that can inhibit myelin repair. In this Opinion article, Yong and colleagues examine such changes and how the ECM could be targeted to promote remyelination in disease.
Nature Reviews Neuroscienceasks five prominent neuroscientists about the goals of several ambitious collaborative projects that have attracted large amounts of funding and media attention in the past year.
Two new studies expand the optogenetic repertoire by showing light-induced inhibition of synaptic release and control of gene transcription and chromatin modifications.
