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Extended reality allows users to be immersed in a virtual environment, with implications for biomedical research and applications. Yuan, Hassan et al. discuss the adoption of extended reality in biomedical research, with a focus on technical advances that overcome current limitations.
Plasmon-mediated chemical reactions use nanostructure-based surface plasmons as mediators to drive chemical reactions. Zhan et al. outline the primary considerations and techniques for designing and constructing plasmonic catalysts and describe the typical methods used to characterize plasmonic catalysts and their reaction mechanisms.
Data analysis relies heavily on computation, and algorithms have grown more demanding in terms of hardware and energy. Monitoring their environmental impacts is and will continue to be an essential part of sustainable research. Here, we provide guidance on how to do so accurately and with limited overheads.
Designing technology for point-of-care use in low- and middle-income countries requires understanding of the underlying barriers that contribute to recalcitrant global problems. The only way to understand those barriers is to work with local experts, otherwise you may wind up solving the wrong problem.
Behavioural genetics examines the underlying factors associated with individual differences in behaviours and capacities. In this Primer, Willoughby et al. discuss the methods used in behavioural genetics analysis, in particular twin studies, genome-wide association studies and statistical modelling.
This PrimeView highlights the techniques used for single-cell pathogen diagnostics to accelerate treatment and contribute to responsible antimicrobial use.
Single-cell pathogen diagnostic tools are increasingly being used to identify and monitor bacterial infections and antimicrobial resistance. In this Primer, Li et al. discuss the assessment, design and implementation of single-cell pathogen diagnostics.
Molecular quantitative trait locus (molQTL) mapping associates genetic variation with molecular traits that can be measured as gene expression, splicing and chromatin accessibility. In this Primer, Aguet et al. discuss the study design and implementation of molQTL mapping in various applications, with a focus on technical developments for functional characterization.
Covalent organic frameworks (COFs) are a class of crystalline porous polymers consisting of highly ordered organic structures formed by polymerization. In this Primer, Tan et al. discuss the design principle, experimental methods, characterization and applications of COFs.
As we close our second volume of Nature Reviews Methods Primers, we look back on our achievements in 2022 and opportunities to better serve our community.
