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  • Proof-of-principle for using phages as vehicles for delivering dominant-sensitive genes into bacteria to reverse resistance.

    • Andrew Jermy
    Research Highlight

  • Sodalis glossinidiushas adapted the PhoPQ two-component system to establish and maintain symbiosis with its tsetse fly host.

    • Andrew Jermy
    Research Highlight

  • A new study published inNature Geneticsreveals the parallel adaptive evolution of a bacterial pathogen during infection of humans and identifies new candidate pathogenicity genes.

    • Sheilagh Molloy
    Research Highlight

  • P. gingivaliscan be viewed as a keystone pathogen owing to its disproportionately large impact on a microbial community relative to its abundance.

    • Sheilagh Molloy
    Research Highlight

  • Our monthly round up of infectious diseases news, which this month includes the origin and spread of an amphibian assassin, turning the tide against HIV, and chicken pox-infected lollipops.

    Disease Watch

  • Two papers provide insight into the roles of the stringent response and H2S in mediating antibiotic tolerance in genetically susceptible bacteria.

    • Andrew Jermy
    Research Highlight

  • Long-chainedS. pneumoniaeis more susceptible to complement-mediated killing.

    • Rachel David
    Research Highlight

  • This month's Genome Watch highlights new perspectives on polygenic adaptation and its consequences for fitness in microbial populations.

    • Tim Downing
    Genome Watch

  • The erythrocyte surface protein basigin is identified as the receptor for Rh5 using a large-scale screen, and probably mediates invasion of allPlasmodium falciparumstrains.

    • Christiaan van Ooij
    Research Highlight

  • A specific nuclear PML isoform functions in the host response to infection by sequestering the viral polymerase of an RNA virus for which replication takes place in the cytoplasm.

    • Andrew Jermy
    Research Highlight