Research Highlights

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  • This study shows that substrate stiffness has an impact on early microcolony formation.

    • Andrea Du Toit
    Research Highlight
  • This study reports a bacterial antiphage protein that contains a NACHT domain, which is also found in metazoan proteins that mediate immunity and inflammation.

    • Andrea Du Toit
    Research Highlight
  • This study reports the identification of an inhibitor of a Toxoplasma gondii myosin motor protein that could be exploited to prevent or treat infections with T. gondii and other apicomplexan parasites.

    • Andrea Du Toit
    Research Highlight
  • This study reports that the resident panicle microbiota in rice modulates host metabolism to prevent Ustilaginoidea virens infection.

    • Andrea Du Toit
    Research Highlight
  • In this study, Brown et al. show that nutrient deprivation increases Plasmodium falciparum survival and tolerance to the antimalarial drug artemisinin.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Gencay et al. develop a cocktail of engineered phages to target clinically relevant Escherichia coli strains.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Tawk et al. explore the impact of infection and inflammation on the adaptations of the commensal population in the mouse gut.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Carfrae et al. show that inhibition of biotin and fatty acid synthesis restores colistin activity against Gram-negative bacteria and prevents colistin resistance.

    • Agustina Taglialegna
    Research Highlight
  • A recent study reports that uropathogenic Escherichia coli infection triggers trained immunity in urinary tract tissue, which affects the immune response to subsequent infections.

    • Ashley York
    Research Highlight
  • This study investigated the environmental microbiomes of cities by sampling urban beehives, providing insight into the surrounding metagenomic landscape that is relevant to beehive and human health.

    • Ashley York
    Research Highlight
  • This study reports a mechanism of norovirus-induced cell death that promotes viral egress.

    • Ashley York
    Research Highlight
  • In this study, Kreitz et al. examine a bacterial extracellular contractile injection system that can deliver diverse proteins into different target cells.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Lubin et al. show that an immature microbiome during weaning affects the development of the immune system and increases the risk of enteric infections in mice.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Stubbendieck et al. show that commensal bacteria Rothia spp. inhibit the growth of the nasal pathobiont Moraxella catarrhalis.

    • Agustina Taglialegna
    Research Highlight
  • This study reports that some bacterial species of the Lachnospiraceae family can suppress colorectal cancer progression by modulating CD8+ T cell immune surveillance activity.

    • Agustina Taglialegna
    Research Highlight
  • This study reports that heat treatment can increase the bactericidal activity of aminoglycosides against multi-drug resistant pathogens.

    • Agustina Taglialegna
    Research Highlight
  • This study reports how fluid flow is linked to changes in gene expression in bacterial pathogens.

    • Andrea Du Toit
    Research Highlight
  • This study shows the development of a chimeric dengue virus bivalent vaccine that generated serotype-specific neutralizing antibodies in vivo.

    • Agustina Taglialegna
    Research Highlight