Research Highlights

In this study, Carfrae et al. show that inhibition of biotin and fatty acid synthesis restores colistin activity against Gram-negative bacteria and prevents colistin resistance.

A recent study reports that uropathogenic Escherichia coli infection triggers trained immunity in urinary tract tissue, which affects the immune response to subsequent infections.

This study investigated the environmental microbiomes of cities by sampling urban beehives, providing insight into the surrounding metagenomic landscape that is relevant to beehive and human health.

This study reports a mechanism of norovirus-induced cell death that promotes viral egress.

In this study, Fackelmann et al. show that microplastics impair the gastrointestinal microbiome of two seabird species.

In this study, Kreitz et al. examine a bacterial extracellular contractile injection system that can deliver diverse proteins into different target cells.

In this study, Lubin et al. show that an immature microbiome during weaning affects the development of the immune system and increases the risk of enteric infections in mice.

In this study, Stubbendieck et al. show that commensal bacteria Rothia spp. inhibit the growth of the nasal pathobiont Moraxella catarrhalis.

This study shows that SARS-CoV-2 restructures host chromatin.

This study reports that some bacterial species of the Lachnospiraceae family can suppress colorectal cancer progression by modulating CD8⁺ T cell immune surveillance activity.

This study reports that heat treatment can increase the bactericidal activity of aminoglycosides against multi-drug resistant pathogens.

This study reports how fluid flow is linked to changes in gene expression in bacterial pathogens.

This study shows the development of a chimeric dengue virus bivalent vaccine that generated serotype-specific neutralizing antibodies in vivo.

A recent study uncovered a relationship between sensory neurons and immune cells in the meninges that facilitates brain invasion by two Streptococcus species and the development of meningitis in mice.

This study reveals a role of contractile injection systems in regulated cell death and developmental processes.

This study analysed sorption, stability and persistence of SARS-CoV-2 RNA in sewers.

This new study reports that a fungal ectosymbiont metabolizes resin monoterpenes of the host tree and that the volatile products possibly function as cues for beetles to locate breeding sites with beneficial fungal symbionts.

This study set out to increase our understanding of how viruses might mediate responses of microbial communities to climate warming.

This study evaluates the efficacy of exogenous pegylated IFNλ in the treatment of patients with COVID-19.

This study shows that the orphan kinesin KLIF is a non-processive dimeric kinesin that bundles microtubules in Trypanosoma brucei.