Research Highlights

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  • Two studies provide insights into the possible roles of viruses in honey bee health and disease.

    • Andrea Du Toit
    Research Highlight
  • Researchers show that Plasmodium falciparum glutamic-acid-rich protein (PfGARP), a 80 kDa antigen expressed on the surface of P. falciparum-infected erythrocytes, is a malaria vaccine candidate for specifically targeting the blood stage of this parasite.

    • Katharine H. Wrighton
    Research Highlight
  • A recent study found that bacterial volatile organic compounds attract springtails to soil-dwelling Streptomyces species, promoting the dispersal of spores.

    • Ashley York
    Research Highlight
  • This study shows that platelets can harbour infectious HIV and transfer it to macrophages.

    • Ursula Hofer
    Research Highlight
  • Two papers now report compound uptake in Mycobacterium tuberculosis by ATP-binding cassette (ABC) exporters, which are usually involved in the export of substrates out of the cell and which could be new drug targets.

    • Andrea Du Toit
    Research Highlight
  • In a new study, Torres, Cadwell and colleagues provide insights into a mechanism whereby host cells deploy extracellular vesicles as decoys that trap and ‘neutralize’ Staphylococcus aureus α-toxin to avoid cell damage.

    • Andrea Du Toit
    Research Highlight
  • This study developed an assay to screen for drugs that inhibit transfer of antimicrobial resistance plasmids between bacteria.

    • Ursula Hofer
    Research Highlight
  • This study finds that phages produced by Pseudomonas aeruginosa form a shield around the bacteria and protect them from antibiotics.

    • Ursula Hofer
    Research Highlight
  • An early effector of Chlamydia pneumoniae induces curvature of the host plasma membrane, which is sensed by a key regulator of endocytosis that is subsequently recruited to promote internalization of the pathogen.

    • Andrea Du Toit
    Research Highlight
  • Researchers have engineered the symbiont Snodgrassella alvi to express double-stranded RNA in honey bees that protects them from pathogens.

    • Katharine H. Wrighton
    Research Highlight
  • Two recent studies provide initial insights into a novel coronavirus that is associated with an outbreak of human respiratory disease.

    • Ashley York
    Research Highlight
  • This study reports the cultivation of a member of the Asgard archaea, which are the closest living relatives of the cells that gave rise to eukaryotes.

    • Ursula Hofer
    Research Highlight
  • A recent study uncovers the molecular mechanism of artemisinin resistance in the most lethal human malaria parasite, Plasmodium falciparum.

    • Ashley York
    Research Highlight
  • Upon host colonization, increased vesiculation accelerates the modulation of the cell surface composition of Vibrio cholerae, which confers resistance to host-derived antimicrobial peptides and bile.

    • Andrea Du Toit
    Research Highlight
  • This study identifies a new family of T6SS-delivered ion-selective pore-forming toxins that is distinct from previously described T6SS effectors.

    • Andrea Du Toit
    Research Highlight
  • Two recent studies find that pioneering bacterial cells use chemotaxis as a navigation strategy to boost range expansion, but colonizing too quickly can leave the population susceptible to invasion by competitors.

    • Ashley York
    Research Highlight
  • Further evidence that measles induce ‘immunological amnesia’ highlight the importance of the vaccination and the need to increase vaccination rates.

    • Andrea Du Toit
    Research Highlight