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Researchers show that Plasmodium falciparum glutamic-acid-rich protein (PfGARP), a 80 kDa antigen expressed on the surface of P. falciparum-infected erythrocytes, is a malaria vaccine candidate for specifically targeting the blood stage of this parasite.
A recent study found that bacterial volatile organic compounds attract springtails to soil-dwelling Streptomyces species, promoting the dispersal of spores.
Two papers now report compound uptake in Mycobacterium tuberculosis by ATP-binding cassette (ABC) exporters, which are usually involved in the export of substrates out of the cell and which could be new drug targets.
In a new study, Torres, Cadwell and colleagues provide insights into a mechanism whereby host cells deploy extracellular vesicles as decoys that trap and ‘neutralize’ Staphylococcus aureus α-toxin to avoid cell damage.
An early effector of Chlamydia pneumoniae induces curvature of the host plasma membrane, which is sensed by a key regulator of endocytosis that is subsequently recruited to promote internalization of the pathogen.
This study reports the cultivation of a member of the Asgard archaea, which are the closest living relatives of the cells that gave rise to eukaryotes.
Upon host colonization, increased vesiculation accelerates the modulation of the cell surface composition of Vibrio cholerae, which confers resistance to host-derived antimicrobial peptides and bile.
Two recent studies find that pioneering bacterial cells use chemotaxis as a navigation strategy to boost range expansion, but colonizing too quickly can leave the population susceptible to invasion by competitors.