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  • Focus |

    When talking about RNAi, it is difficult to separate biology from technology. And so this Collection on RNA interference includes Reviews and Research Highlights on both aspects of this topic.

  • Focus |

    The field of RNA is defined by the many different RNA species that exist in nature. The most well-known and most diverse species — messenger RNA — carry the genetic code, which is to be translated into proteins.

  • Focus |

    This Collection on systems biology, which contains a selection of recent reviews, perspectives and research highlights, is designed to provide an introduction to this emerging cross-disciplinary field.

  • Focus |

    The availability of whole genome sequences for many organisms has resulted in a rush to elucidate the function of the products of these genomes and their role in health and disease. But deciphering the complexity of the proteome is a daunting task, and the application of proteomics is still very much in its infancy.

  • Focus |

    Historically, plant cell biology has been studied using more traditional genetic approaches, but more recently, biochemistry, and state-of-the-art imaging and other cell biology techniques have contributed to the wealth of exciting data in this broad field.

  • Focus |

    Cytoskeletal elements are essential mediators of signalling and can influence many cellular processes through this capacity. Accordingly, there has been a huge drive to understand the intricacies of cytoskeletal dynamics — from what regulates cytoskeletal elements to their effects on cells — and the rapid advances being made in cell and molecular biology approaches, and, in particular, in imaging techniques, are allowing us to scrutinize these processes.

  • Focus |

    Since the early studies of the 17th century, microscopy has played a vital role in biological discovery − it enabled Robert Hooke to describe cells and Antonie van Leeuwenhoek to discover bacteria. Four centuries later, microscopy techniques remain at the centre of cell-biological research.

  • Focus |

    Nature Cell BiologyandNature Reviews Molecular Cell Biologyare pleased to present a joint supplement on imaging in cell biology. The specially commissioned articles focus on key advances in imaging techniques, which allow us to follow cell-biological events ranging from the dynamics of single molecules in living cells to the development of whole organisms.

  • Focus |

    Calcium is a crucial intracellular signal that is responsible for regulating many cellular processes, including embryonic development, cell proliferation, apoptosis, cardiac contractility, and learning and memory. This Focus brings together a selection of relevant articles from across Nature Research journals.

  • Focus |

    In this Focus, we look at several well-established signalling pathways as well as those that have recently emerged or recently been proposed. It is not surprising, therefore, that the signalling field often seems overwhelming, and our aim is to make it accessible to everyone.

  • Focus |

    In this Focus, we look at the various mechanisms behind cell death in general, and apoptosis in particular.

  • Focus |

    This Focus contains a selection of review, perspective and research highlight articles on stem cells from the Nature Reviews journals.