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It is well established that marketing of unhealthy food is highly prevalent and has a detrimental effect on children’s eating behaviours and diet. A new study highlights how a new type of social media influencer — children themselves — is contributing to this phenomenon.
This Review highlights how obesity and impaired metabolic health increase complications and mortality in coronavirus disease 2019 (COVID-19) and summarizes the consequences of infection with severe acute respiratory syndrome coronavirus 2 for organ function. In addition, there is a discussion on the implications of the COVID-19 pandemic for the obesity pandemic.
This Review examines the evidence that β-cells are active participants in the dialogue with the immune system during the development of type 1 diabetes mellitus. The authors suggest that therapies targeting β-cell health, vitality and function might prove essential, in combination with immunotherapy, to change the course of events leading to β-cell destruction.
This Review summarizes the physiological functions, pharmacology and clinical studies of G protein-coupled receptors that are specific for lipid metabolite ligands. The challenges associated with the clinical development of therapeutics for type 2 diabetes mellitus that target these G protein-coupled receptors are also discussed.
This Review summarizes clinical practice for differentiated thyroid cancer, highlighting advances in therapy, including surgery and the use of radioactive iodine, as well as improved diagnostic tools and prognostic classifications. Different management strategies for patients with low-risk, intermediate-risk and high-risk differentiated thyroid cancer are discussed.
