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Decade in review—thyroid disease

The endocrinology of thyroid disease from 2005 to 2015

The past decade has seen exciting progress in the field of thyroid disease, especially in the evaluation of thyroid nodules, the genomic characterization of carcinomas and the treatment of carcinomas after surgery. An improved understanding of hyperthyroidism during pregnancy, as well as the causes of 'low T3 syndrome' and consumptive hypothyroidism have also been achieved.

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References

  1. Cibas, E. S. & Ali, S. Z. The Bethesda system for reporting thyroid cytopathology. Thyroid 19, 1159–1165 (2009).

    Article  Google Scholar 

  2. Alexander, E. K. et al. Multicentre clinical experience with the Afirma gene expression classifier. Clin. Endocrinol. Metab. 99, 19–25 (2014).

    Article  Google Scholar 

  3. Xing, M. et al. Association between BRAF V600E mutation and recurrence of papillary thyroid cancer. Clin. Oncol. 33, 42–50 (2015).

    Article  Google Scholar 

  4. Ho, A. L. et al. Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. N. Engl. J. Med. 368, 623–632 (2013).

    Article  CAS  Google Scholar 

  5. Cancer Genome Atlas Research Network. Integrated genomic characterization of papillary thyroid carcinoma. Cell 159, 676–690 (2014).

  6. Schlumberger, M. et al. Strategies of radioiodine ablation in patients with low-risk thyroid cancer. Tumeurs de la Thyroïde Refractaires Network for the Essai Stimulation Ablation Equivalence Trial. N. Engl. J. Med. 366, 1663–1673 (2012).

    Article  CAS  Google Scholar 

  7. Mallick, U. et al. Ablation with low-dose radioiodine and thyrotropin alfa in thyroid cancer. N. Engl. J. Med. 366, 1674–1685 (2012).

    Article  CAS  Google Scholar 

  8. Maynard, M. A. et al. Thyroid hormone inactivation in gastrointestinal stromal tumors. N. Engl. J. Med. 37, 1327–1334 (2014).

    Article  Google Scholar 

  9. Andersen, S. L., Olsen, J., Wu, C. S. & Laurberg, P. Severity of birth defects after propylthiouracil exposure in early pregnancy. Thyroid 24, 1533–1540 (2014).

    Article  CAS  Google Scholar 

  10. Wajner, S. M. et al. IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells. J. Clin. Invest. 121, 1834–1845 (2011).

    Article  CAS  Google Scholar 

Download references

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Correspondence to P. Reed Larsen.

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Larsen, P. The endocrinology of thyroid disease from 2005 to 2015. Nat Rev Endocrinol 11, 634–636 (2015). https://doi.org/10.1038/nrendo.2015.169

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