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In 1923, Kimball and Murlin published work that identified a substance in pancreatic extracts that caused hyperglycaemia, which they named glucagon. A century later, we now know the importance of this hormone in human physiology and disease, and drugs targeting the glucagon receptor family have been developed to treat metabolic diseases.
Adipose tissue is a complex organ that has crucial endocrine and metabolic functions in mammalian physiology. A new Article Series aims to collate adipose tissue content from Nature Reviews Endocrinology and provide a useful resource for researchers working in this field.