Review Articles, News & Views, Perspectives, Hypotheses, Analyses and Review

The IKK NF-κB system: a treasure trove for drug development

• Michael Karin
• Yumi Yamamoto
• Q. May Wang

Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model

• Anthony W. Norman
• Mathew T. Mizwicki
• Derek P. G. Norman

Tissue microarrays in drug discovery

• Guido Sauter
• Ronald Simon
• Kenneth Hillan

GLIA: A novel drug discovery target for clinical pain

• Linda R. Watkins
• Steven F. Maier

Paediatric clinical trials: redressing the imbalance

• Mark S. Schreiner

Opportunities in somatostatin research: biological, chemical and therapeutic aspects

• Gisbert Weckbecker
• Ian Lewis
• Christian Bruns

Neuropeptide gene polymorphisms and human behavioural disorders

• Akio Inui

COX-2 and beyond: approaches to prostaglandin inhibition in human disease

• Garret A. FitzGerald

Ace revisited: A new target for structure-based drug design

• K. Ravi Acharya
• Edward D. Sturrock
• Mario R. W. Ehlers

New targets for allergic rhinitis — a disease of civilization

• Stephen T. Holgate
• David Broide

Therapeutic angiogenesis in cardiovascular disease

• Michael Simons
• J. Anthony Ware

Targeting the Nogo Receptor to Treat Central Nervous System Injuries

• Daniel H. S. Lee
• Stephen M. Strittmatter
• Dinah W. Y. Sah

Therapeutic potential of venom peptides

• Richard J. Lewis
• Maria L. Garcia

Protecting your inventions: the patent system

• Philip M. Webber

HIF-1 as a target for drug development

• Amato Giaccia
• Bronwyn G. Siim
• Randall S. Johnson

Antiplatelet therapy: in search of the 'magic bullet'

• Shaun P. Jackson
• Simone M. Schoenwaelder

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

• William Lewis
• Brian J. Day
• William C. Copeland

Trends in development and approval times for new therapeutics in the United States

• Janice M. Reichert

Therapeutic antagonists and conformational regulation of integrin function

• Motomu Shimaoka
• Timothy A. Springer

Recent advances in the discovery and delivery of vaccine adjuvants

• Derek T. O'Hagan
• Nicholas M. Valiante