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Mapping regulatory regions of chromatin by analyzing their sensitivity to nuclease using microarrays. Artistic illustration by Erin Boyle based on images provied by Francis Collins. Articles p503 and p511
DNase-chip and DNase-array: similar names for two different new approaches that give a genomic perspective to the conventional DNase I hypersensitivity assay used to measure chromatin accessibility.
The main application of microarrays is gene expression analysis, but other uses for these arrays continue to grow in popularity. Laura Bonetta reports on the use of this technology to analyze other entities, from carbohydrates to tissue samples.