News & Comment

A panel of advanced methods reveals that retrotransposable elements are more prevalent than suspected in human genomes.

Visualization of newly synthesized proteomes using conventional fluorescence microscopy reveals the local nature of protein translation.

Overall safety is increasing, but new safety hazards, such as repetitive stress injuries and potential toxicities from nanoparticles, are coming under closer scrutiny.

Nanoscale robots can be programmed to walk a DNA origami track.

Raw data of millions of sequences used to assemble the reference genomes of ten organisms are analyzed in search of mismatches indicative of editing events. Findings include candidate sites for in vivo DNA and RNA editing, and a common sequencing error.

A technique combining laser and electron pulses is used to achieve nanometer and femtosecond resolution in biological imaging.

Live-cell time-lapse imaging of somatic cells undergoing reprogramming raises interesting questions about the mechanism of the process.

New strategies expand the genetic toolkit for transgene expression, lineage tracing and mosaic analysis of gene function in flies and mammalian cells.

Understanding how cloud computing can serve the scientific community is a research question in its own right and one that researchers—with the help of funders—should address.

Fly brains light the way for neurobehavioral circuits.

Researchers synthesized the first functional synthetic bacterial genome; repeating this feat with different bacteria will require further methodological development.

To keep pace with accelerating sequencing machines, genomics researchers clean house and move toward the cloud.

A new technique for transcriptome-wide isolation of RNAs bound to specific proteins reveals, with high resolution, the location of RNA-binding proteins on their target RNAs.

Applying technology developed for next-generation DNA sequencing to study translation, researchers watch individual ribosomes string together amino acids in real time.